OBJECTIVE To investigate the evolution of pulmonary hypertension, the pathological changes of pulmonary arteries, and the expression of VEGFmRNA and eNOSmRNA of pulmonary arterial endothelial cells in immature rabbits treated with intratracheal bleomycin (BLM). METHODS Immature rabbits were divided into control and BLM group. Two and four weeks after intratracheal normal saline or BLM injecti...

Our laboratory has developed a method of particle exposure whereby anesthetized rats intratracheally inhale, at a regulated breathing rate and pressure, an aerosolized test material. This method is capable of delivering considerable doses in a short time period and, unlike the commonly used method of intratracheal instillation, does so with an even particle distribution throughout the lung. Ear...

DESCRIPTION Infasurf® (calfactant) Intratracheal Suspension is a sterile, non-pyrogenic lung surfactant intended for intratracheal instillation only. It is an extract of natural surfactant from calf lungs which includes phospholipids, neutral lipids, and hydrophobic surfactant-associated proteins B and C (SP-B and SP-C). It contains no preservatives. Infasurf is an off-white suspension of calfa...

AIM: The article has researched cell morphological changes of phagocytic system’s experimented animals by influence cool-rock dust phisical loading basis.
 METHODS: activity in combined operation destructive the cells and lowering vital capacity was investigated.
 RESULTS: taken results let cosider structure-functional condition phagocytal unfavorable industrial factors.
 CONCLUS...