نتایج جستجو برای: intraperitoneal bupivacaine

تعداد نتایج: 23477  

Journal: :Turkish journal of anaesthesiology and reanimation 2016
Ayşe Ünal Düzlü Berrin Günaydın Murat Kadir Şüküroğlu İsmail Tuncer Değim

OBJECTIVE We aimed to compare the possible controlled release profile of multilamellar liposomal bupivacaine formulations with non-liposomal forms in artificial cerebrospinal fluid (CSF) under in vitro conditions. METHODS Liposome formulations were prepared using a dry-film hydration method. Then, an artificial CSF-buffered solution was prepared. Bupivacaine base with liposomal bupivacaine ba...

Journal: :American journal of physiology. Cell physiology 2010
Daniela Danieli-Betto Samantha Peron Elena Germinario Marika Zanin Guglielmo Sorci Susanna Franzoso Dorianna Sandonà Romeo Betto

Sphingosine 1-phosphate (S1P) is a bioactive lipid known to control cell growth that was recently shown to act as a trophic factor for skeletal muscle, reducing the progress of denervation atrophy. The aim of this work was to investigate whether S1P is involved in skeletal muscle fiber recovery (regeneration) after myotoxic injury induced by bupivacaine. The postnatal ability of skeletal muscle...

2016
Jeffrey Gadsden William J. Long

BACKGROUND Liposome bupivacaine is a prolonged-release bupivacaine formulation indicated for single-dose administration into the surgical site to produce postsurgical analgesia. METHODS An overview of time to onset of analgesia observed with liposome bupivacaine in human studies is provided, as well as a summary of data from pharmacokinetic studies including those that assessed pharmacokineti...

Journal: :Anesthesia and analgesia 2011
Marcio G Kiuchi Gisele Zapata-Sudo Margarete M Trachez Douglas Ririe Roberto T Sudo

BACKGROUND The susceptibility of children and newborns to cardiotoxicity from racemic bupivacaine, RS(±)-bupivacaine, is controversial. Some studies indicate that newborns can sustain higher bupivacaine plasma levels than adults, without severe toxicity. In this study, we compared the influence of age on cardiotoxicity from RS(±)-bupivacaine and S(-)-bupivacaine in rats. The effects of these lo...

2015
Girish P Joshi Gary Patou Vladimir Kharitonov

BACKGROUND This report presents results from four preclinical studies evaluating safety and pharmacokinetics (PKs) of liposome bupivacaine following intravascular (intravenous [IV], intra-arterial [IA]), epidural, and intrathecal administration in dogs. METHODS Intravascular administration was initially tested in a pilot study to determine maximum tolerated doses, and then in an expanded stud...

Journal: :journal of family and reproductive health 0
azin alavi reproductive health research center, shahid beheshti university of medical sciences and health services, tehran, iran saghar salehpour reproductive health research center, shahid beheshti university of medical sciences and health services, tehran, iran mahnaz narimani department of anesthesiology and pain research institue, shahid beheshti university of medical sciences and health services, tehran, iran

objective: this study investigated the efficacy of bupivacaine wound infusion for pain control and opioid sparing effect after cesarean delivery. materials and methods: we conducted a randomized double blind, placebo controlled clinical trial on 60 parturients undergoing cesarean section at a university hospital in tehran. patients were randomized to receive a pump infusion system that was fill...

Journal: :jundishapur journal of natural pharmaceutical products 0
nader saki hearing and speech research center, ahvaz jundishapur university of medical sciences, ahvaz, ir iran neda alsadat jasemi hearing and speech research center, ahvaz jundishapur university of medical sciences, ahvaz, ir iran lila mashali hearing and speech research center, ahvaz jundishapur university of medical sciences, ahvaz, ir iran maziar baikpour hearing and speech research center, ahvaz jundishapur university of medical sciences, ahvaz, ir iran soheila nikakhlagh hearing and speech research center, ahvaz jundishapur university of medical sciences, ahvaz, ir iran; hearing and speech research centre, ahvaz jundishapur university of medical sciences, ahvaz, ir iran. tel: +98-9161111395, fax: +98-6132921838 hasan abshirini hearing and speech research center, ahvaz jundishapur university of medical sciences, ahvaz, ir iran

conclusions considering that tonsillectomy is one of the most common surgeries in children and produces a lot of pain, using a low risk medicine such as bupivacaine to recover child as soon as possible seems reasonable. results patients aged 4 to 13 years. the amount of postoperative pain was obviously less in the bupivacaine group than the other group. the mean time of postoperative fluid inta...

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