Objective: To establish whether a mother’s intrahepatic cholestasis of pregnancy (ICP) has connections to her daughter’s health. Design: A retrospective study of daughters to ICP mothers. Setting: The region of Tampere University Hospital in Finland. Subjects: The study population comprised 575 women diagnosed with ICP during at least one pregnancy in the obstetric department of Tampere Univers...

Intrahepatic cholestasis of pregnancy (ICP) is associated to unpredictable fetal risks. The mechanisms underlying poor perinatal outcomes are unknown. Intracranial fetal hemorrhage is a possible complication of ICP. A young patient presented with mild ICP and severe transaminases elevation, at 32 weeks of pregnancy. Ultrasound revealed fetal ventriculomegalia probably secondary to intracranial ...

The occurrence of cholestasis during pregnancy may be due to several disorders. These include pregnancyspecific diseases, like intrahepatic cholestasis of pregnancy(ICP), as well as to other causes such as oligosymptomatic choledocolitiasis, viral hepatitis and other underlying liver disorders like primary biliary cirrhosis. In recent years, the discovery of mutations in hepatobiliary transport...

Introduction: Intrahepatic cholestasis of pregnancy (ICP) is the most common pregnancy-related liver disease. It characterized by persistent pruritus, usually occurring after 30 weeks pregnancy, and elevated levels bile acids transaminases, which decrease over course 2-3 postpartum. [1,2]The occurrence ICP in mother may be associated with significant complications fetus, such as: preterm labor,...

Background:Obstetric cholestasis, or intrahepatic cholestasis of pregnancy (ICP), is a liver disease that usually presents in the third trimester pregnancy. It characterized by pruritis associated with elevated enzymes and bile acids. This condition can have potentially serious effects on fetus due to buildup serum acids resulting from obstruction flow.
 Case Overview:A 28-year-old patient...

Certain dermatoses are specifically seen in pregnancy or postpartum period. It is therefore important for the clinicians to recognize and treat these cutaneous disorders to minimize maternal and fetal morbidity. The commonest pregnancy related dermatoses was polymorphic eruption of pregnancy seen in 22% patients, prurigo of pregnancy was seen in 7% patients, pemphigoid gestationis was seen in 3...

QUESTION Some of my pregnant patients complain about pruritus. Are there conditions in pregnancy that present with pruritus that might put the mother or fetus at risk? ANSWER Although most cases of pruritus can be attributed to itchy dry skin, there are conditions unique to pregnancy that involve pruritus as a leading symptom. These include pemphigoid gestationis, pruritic urticarial papules ...