Intracranial hemorrhage is the third most frequent cause of cerebrovascular disease, but few genetic risk factors have been associated with its development. Recently, it has been reported that some polymorphisms that affect clotting factors increase the risk for thrombosis. However, reports have analyzed the effect of polymorphisms influencing the hemostatic state in bleeding disorders insuffic...

BACKGROUND AND PURPOSE Intracranial hemorrhage is the most devastating complication of anticoagulation. Outcomes associated with different sites of intracranial bleeding occurring with warfarin versus dabigatran have not been defined. METHODS Analysis of 18 113 participants with atrial fibrillation in the Randomized Evaluation of Long-term anticoagulant therapY (RE-LY) trial assigned to adjus...

Maternal smoking during pregnancy is associated with greater rates of premature deliveries, low birth weight, perinatal morbidity and mortality, and impaired intellectual development. It also causes a three-fold greater risk for intracranial hemorrhage in neonates. To our knowledge no neonatal case with intracranial hemorrhage and hematuria related to heavy maternal smoking has been published t...

Intrahepatic cholestasis of pregnancy (ICP) is associated to unpredictable fetal risks. The mechanisms underlying poor perinatal outcomes are unknown. Intracranial fetal hemorrhage is a possible complication of ICP. A young patient presented with mild ICP and severe transaminases elevation, at 32 weeks of pregnancy. Ultrasound revealed fetal ventriculomegalia probably secondary to intracranial ...

BACKGROUND AND PURPOSE Intracranial hemorrhage is the most serious outcome for brain arteriovenous malformations. This study examines associations between venous characteristics of these lesions and intracranial hemorrhage. MATERIALS AND METHODS Statistical analysis was performed on a prospectively maintained data base of brain AVMs evaluated at an academic medical center. DSA, CT, and MR ima...

A 34 day-old girl infant was admitted for poor feeding and cholestasis. She had a bulging fontanelle, with no evidence of intracranial infection or hemorrhage. Investigations demonstrated that she had galactosemia. Computed tomographic scans demonstrated the presence of diffuse cerebral edema. After treatment the edema resolved.

 Background and Importance: Coronavirus 19 is caused by the SARS-COV-2 virus. The primary target of the virus is the respiratory system, but it can also affect other systems of the body, such as the cardiovascular system and the Central Nervous System )CNS).  Case Presentation: In this study, we introduce an 83-year-old man who referred due to reduced level of consciousness and hemiparesis ...