UNLABELLED The most common etiologies of tympanic membrane perforation are infections and trauma. OBJECTIVE The objective of the present study was to assess the healing of traumatic tympanic membrane perforation in rats. METHODS The tympanic membrane from male Wistar rats was perforated in the anterior and posterior portions to the handle of the malleus. Five tympanic membranes were evaluat...

Introduction: 17&beta-Estradiol modulates nociception by binding to the estrogenic receptors and also by allosteric interaction with other membrane-bound receptors like glutamate and GABAA receptors. In addition to its autonomic functions, paragigantocellularis lateralis (LPGi) is involved in the pain modulation, too. The aim of the current study was to investigate the involvement of the membra...

background and objective: amygdala contains central nucleus which is the region rich of γ-aminobutyric acid (gaba-a) receptors and plays a key role in modulating behavior and sleep homeostasis. furthermore, dysfunction of amygdala probably contributes to anxiety and mood disorders. in this study, we evaluated the association between acute sleep deprivation (asd) and anxiety through gaba-a recep...

PURPOSE To determine specific criteria that can be used to define normal versus abnormal MR contrast enhancement of the facial nerve. METHODS Twenty-three patients with acute unilateral inflammatory peripheral facial nerve palsy were examined on a 1.5-T MR using multiplanar T1-weighted spin-echo sequences before and after injection of gadopentetate dimeglumine. These MR patterns were compared...

Objective: To determine the effectiveness of Intratympanic Dexamethasone with Lidocaine in control idiopathic tinnitus.
 Study Design: Randomized trial (Clinical Trials. gov Identifier: NCT04798391).
 Place and Duration Study: ENT Department, PAF Hospital, Sargodha Pakistan, from Apr 2017 to Jul 2019.
 Methodology: 264 consenting patients unilateral tinnitus presenting at Departm...