Abstract According to the AISC Seismic Provisions for Structural Steel Buildings (AISC341‐16) and EC8, inelastic rotation demand at design story drift is limited 0.08 rad I‐shape shear links in eccentrically braced frames (EBFs). Numerical studies on EBF archetypes show that single‐sided demands can be much higher than limiting value. In addition, these fail due low‐cycle fatigue (LCF) which de...

OBJECTIVE Nursing homes that are not meeting quality standards are cited for deficiencies. Before 1995, the only recourse for a nursing home was a formal appeal process, which is lengthy and costly. In 1995, the Centers for Medicare & Medicaid Services instituted the Informal Dispute Resolution (IDR) process. This study presents for the first time national statistics about the IDR process and a...

This study presents the numerical implementation of a semi-active control system used to reduce lateral displacements in framed structures under seismic loads. To manage forces structures, two controllable fluid devices called magnetorheological (MR) dampers were used, and fuzzy logic (FL) algorithm was employed determine optimal forces. The FL controller has been programmed based on set 49 inf...

This study emphasizes a new strengthening scheme for seismically vulnerable flat plate-column connections in existing structures. An experimental investigation on series of three half-scaled interior was conducted to explore the effectiveness proposed seismic method using postinstalled RC wing walls and analyze punching shear capacity connections. focuses typical plate structures constructed lo...

This study addresses an alternative use of viscous dampers (VDs) associated with buckling restrained braces (BRBs) as innovative seismic protection devices. For this purpose, 4-, 8- and 12-story steel bare frames were designed 6.5 m equal span length 4 story height. Thereafter, they seismically improved by mounting the VDs BRBs in three patterns, namely outer bays, inner all bays over frame hei...

We present IDR(s), a new family of efficient, short-recurrence methods for large nonsymmetric systems of linear equations. The new methods are based on the Induced Dimension Reduction (IDR) method proposed by Sonneveld in 1980. While state-ofthe-art methods such as Bi-CGSTAB require at most 2N matrix-vector products to compute an exact solution in exact arithmetic, IDR(s) requires at most N + N...

Auto-antibodies (aAbs) to thyroid peroxidase (TPO) interact with a restricted immunodominant region (IDR) divided into two overlapping regions A and B. Among the five major regions structuring the IDR/B, regions 210-225, 353-363, 549-563, 713-720 and 766-775, region 353-363 constitutes an important anchor point for the binding of TPO-specific aAbs in sera from Hashimoto's and Graves' patients. ...

The effect of oxidants on voltage-dependent K+ currents was examined in mouse colonic smooth muscle cells. Exposure to either chloramine-T (Ch-T), an agent known to oxidize both cysteine and methionine residues, or the colon-specific oxidant monochloramine (NH2Cl) completely suppressed the transient outward K+ current (Ito) while simultaneously enhancing the sustained delayed rectifier K+ curre...

The influence of the surfactants of sodium lauryl sulfate (SLS) and Tween 80 on carbamazepine-nicotinamide (CBZ-NIC) cocrystal solubility and dissolution behaviour has been studied in this work. The solubility of the CBZ-NIC cocrystal was determined by measuring the eutectic concentrations of the drug and the coformer. Evolution of the intrinsic dissolution rate (IDR) of the CBZ-NIC cocrystal w...

BACKGROUND AND OBJECTIVES Patients with refractory acute myeloid or lymphoid leukemia (AML, ALL) were treated with a high-dose regimen comprising idarubicin (IDR) plus short-course cyclosporin A (CsA) as multidrug resistance type-1 (MDR1) blocking agent. The principal aim was to define the maximum tolerated dose (MTD) of IDR, which is reported to be a less MDR1-sensitive anthracycline. The shor...