نتایج جستجو برای: interlukin

تعداد نتایج: 170  

Journal: :Molecules 2017
Yahui Hu Nandani Darshika Kodithuwakku Lin Zhou Chengyuan Li Dan Han Weirong Fang Jihua Liu Yunman Li

Background: Tumor compression-induced pain (TCIP) is a complex pathological cancer pain. Spinal glial cells play a critical role in maintenance of cancer pain by releasing proinflammatory cytokines and chemokines. In this study, we verified the role of levo-corydalmine (l-CDL) on TCIP. Methods: Spontaneous pain, paw withdrawal threshold and latency were assessed using TCIP mouse model. Immunofl...

2013
Iman H. Kamel E. Nassef Hanaa H. Ahmed

Childhood obesity and its complications have become a very serious public health concern and threat. Obesity confers increased risk for cardiovascular diseases as a result of accumulation of visceral fat, which alters metabolism and insulin sensitivity. The objective of this study is to identify, correlate and validate certain biomarkers for detecting obesity in Egyptian children. Thirty patien...

2010
Sang Kyu Lee Dong Ju Lee Tae Won Jeon Gyu Sub Ko Se Hyun Yoo Hyun Woo Ha Mi Jeong Kang Wonku Kang Sang Kyum Kim Tae Cheon Jeong

Halogenated organic compounds, such as 1-bromobutane (1-BB) , have been used as cleaning agents, agents for chemical syntheses or extraction solvents in workplace. In the present study, immunotoxic effects of 1-BB and its conjugation with glutathione (GSH) were investigated in female BALB/c mice. Animals were treated orally with 1-BB at 375, 750 and 1500 mg/kg in corn oil once for dose response...

Journal: :Dental materials : official publication of the Academy of Dental Materials 2007
Keyvan Moharamzadeh Richard Van Noort Ian M Brook Andy M Scutt

OBJECTIVES The aim of this study was to evaluate and compare the biological effects of three resin monomers on three human gingival fibroblast (HGF) cell lines and immortalised human keratinocytes. METHODS Primary HGFs and HaCaT keratinocytes were cultured for 24h and grown to sub-confluent monolayers. Resin monomers were dissolved in dimethyl sulphoxide (DMSO) and diluted with culture medium...

2011
Ruiping Zhang Shengli Xu Yanning Cai Ming Zhou Xiaohong Zuo Piu Chan

Abundant evidence has suggested that neuroinflammation participates in the pathogenesis of Parkinson's disease (PD). The emerging evidence has supported that microglia may play key roles in the progressive neurodegeneration in PD and might be a promising therapeutic target. Ganoderma lucidum (GL), a traditional Chinese medicinal herb, has been shown potential neuroprotective effects in our clin...

2014
Yue Yu Jennifer Suehyun Lee Ning Xie Estelle Li Antonio Hurtado-Coll Ladan Fazli Michael Cox Stephen Plymate Martin Gleave Xuesen Dong

BACKGROUND Reciprocal interactions between epithelium and stroma play vital roles for prostate cancer development and progression. Enhanced secretions of cytokines and growth factors by cancer associated fibroblasts in prostate tumors create a favorable microenvironment for cancer cells to grow and metastasize. Our previous work showed that the progesterone receptor (PR) was expressed specifica...

2016
Abbas Kiani-Esfahani Sedigheh Kazemi Sheykhshabani Maryam Peymani Motahare-Sadat Hashemi Kamran Ghaedi Mohammad Hossein Nasr-Esfahani

OBJECTIVE Annexin A1 (ANXA1) is suggested to have anti-inflammatory function. However, the precise function of ANXA1 has remained unclear. In this study, we therefore examined the potency of ANXA1 in regulating reactive oxygen species (ROS) production and suppressing pro-inflammatory responses in PC12 cells induced by 1-methyl-4-phenylpyridinium (MPP+). MATERIALS AND METHODS In this experimen...

2014
Rongyi Chen Meng Fu Guoxue Zhang Ying Zhou Shaojun Zhu Juanjuan Liu Dong Wang Anmei Deng Zhipeng Wang

Rac1 is a member of the Rho family of small GTPases that control cells proliferation, differentiation, migration, and inflammation. Rac1 is crucial in tumorigenesis and development. Keratin17 and CD11b+Gr1+ cells are considered to regulate skin inflmmation. Here we discuss the regulation of Rac1 on skin tumor formation and its relationship. In samples from human skin squamous cell carcinoma (SC...

2017
Yang Huang Zi Ye Hang Li Zhaohui Li

PURPOSE To further investigate the pathogenesis of late-onset capsular block syndrome (CBS) and to evaluate the safety of surgical treatment. METHODS Seven patients diagnosed with late-onset CBS were retrospectively analyzed. Anterior chamber depth (ACD), intraocular pressure (IOP), refractive diopter, and best-corrected visual acuity (BCVA) before and after surgery were recorded. The opaque ...

2016
Chao Zhang Lan-Hong Zhang Yin-Fang Wu Tian-Wen Lai Hai-Sheng Wang Hui Xiao Luan-Qing Che Song-Min Ying Wen Li Zhi-Hua Chen Hua-Hao Shen

Suhuang antitussive capsule (Suhuang), a traditional Chinese medication, is found effective in treating chronic cough and cough variant asthma (CVA). This study aimed to determine the possible effects and underlying mechanisms of Suhuang on chronic ovalbumin (OVA)-induced airway hyperresponsiveness (AHR), inflammation, and remodeling in mice. Mice were randomly assigned to six experimental grou...

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