background: growth factors play a major part in wound healing in many tissues including the periodontium. transforming growth factor-β1 (tgf-β1) is one of these factors present in the gingival crevicular fluid. in addition, it is considered as one of the most important anti-inflammatory cytokines. interleukin-1β is a proinflammatory cytokine that presents itself in gingival inflammation and the...

objective: stevioside is a natural non-caloric sweetener which has been reported to have anti-inflammatory activity.  the aim of  the present study was to examine in vitro and in vivo effects of  stevioside on rats  plasma levels of tumor necrosis factor- α (tnf-α),  interleukin-1β (il-1β), tnf-α and il-1β release from lipopolysaccharide(lps)-stimulated rat peripheral blood mononuclear cells (p...

background and objective: host genetic factors such as cytokine gene polymorphisms as well as helicobacter pylori (h. pylori) infection have been found to be associated with gastric cancer risk . interleukin 1 is a pro-inflammatory cytokine involved in h. pylori-induced gastric inflammation. therefore, we analyzed the association between il-1β and il-1-rn polymorphisms and gastric cancer in per...

Background: Cytokines are suggested to play a role in periodontitis. Objective: To determine and compare the levels of Interleukin-1 beta (IL-1β) and Tumor necrosis factor alpha (TNF-α) in gingival crevicular fluid (GCF) samples amongst healthy individuals and  those with chronic periodontitis. Further to compare the GCF cytokine levels in three genotype classes defined by the respective gene p...

Lung metastasis is the major cause of breast cancer-related mortality. The neutrophil-associated inflammatory microenvironment aids tumor cells in metastatic colonization lungs. Here, we show that tumor-secreted protease cathepsin C (CTSC) promotes breast-to-lung by regulating recruitment neutrophils and formation neutrophil extracellular traps (NETs). CTSC enzymatically activates membrane-boun...

background: endometrial secretion analysis is a non-invasive and promising method in evaluation of endometrial receptivity. objective: the aim of the present study was to assess the relationship between the success rate of ivf procedures and some endometrial secretion cytokines, including interleukin-1β (il-1β), tumor necrosis factor (tnf-α), interferon gamma-induced protein 10 (ip-10), and mon...

Abstract Objective To observe the anti-inflammatory effect, as well effect on expression of microtubule-associated protein light chain 3B (LC3B) and Beclin-1 herbal cake-partitioned moxibustion in rats with experimental autoimmune thyroiditis (EAT). Methods Female Sprague-Dawley were randomly divided into a normal group modeling group. The EAT rat model was prepared by combination antigen immun...

Background: Growth factors play a major part in wound healing in many tissues including the periodontium. Transforming growth factor-β1 (TGF-β1) is one of these factors present in the gingival crevicular fluid. In addition, it is considered as one of the most important anti-inflammatory cytokines. Interleukin-1β is a proinflammatory cytokine that presents itself in gingival inflammation and the...

This study was aimed to monitor water pullution of Uzuncayir Dam Lake using the changes of IL-6, IL1β and TNF-α levels in Capoeta umbla (Heckel, 1843) liver tissue at ten stations in March and September 2011. In this study C. umbla (Heckel, 1843) was used as the indicator organism. Tumor necrosis factor-α (TNF-α), interlekuin1β (IL-1β) and interleukin-6 (IL-6) levels were determined in samples ...

BACKGROUND Salivary mRNA biomarkers can exhibit significant variation over time. The purpose of this study was to investigate the pattern and magnitude of variation of salivary mRNA biomarkers and to explore the effect of performing replicate assays and multiple sampling on the dispersion of salivary biomarkers. METHODS Salivary interleukin-8 (IL-8) and interleukin-1β (IL-1β) mRNAs, developed...