More than 1,300 different mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) are the cause for cystic fibrosis. CFTR is in charge of proper secretion and absorption of electrolytes, and thus the disease is characterized by defective epithelial Cl(-) secretion and enhanced Na(+) absorption. Recent studies show that CFTR interacts with other proteins via PDZ domains.

In this paper, we describe applications built on top of the Open University’s linked data platform (data.open.ac.uk), from the point of view of the way they implement particular forms of interactions with linked data. We especially focus on the common advantages and pitfalls in interacting with linked data that these applications illustrate, from both the end-users’ and the developer’s perspect...

Interacting, multi-robot systems show increasing promise for advances in exploration and defense applications. Here, we model a non-linear system of self-propelled individuals interacting via a pairwise attractive and repulsive potential. Depending on the interaction parameters, the agents may disperse, accumulate into self-organizing structures such as flocks and vortices, or collapse onto the...

Service-oriented architectures propose loosely coupled interacting services as building blocks for distributed applications. Since distributed services differ from traditional monolithic software systems, novel testing methods are required. Based on the specification of a service, we introduce an approach to automatically generate test cases for blackbox testing to check for conformance between...

In this paper, we describe applications built on top of the Open University’s linked data platform (data.open.ac.uk), from the point of view of the way they implement particular forms of interactions with linked data. We especially focus on the common advantages and pitfalls in interacting with linked data that these applications illustrate, from both the end-users’ and the developer’s perspect...

3.2 Levels of resolution We use the metaphor of radiation to determine the "value" of certain content. Therefore, one can adapt one's sensitivity to radiation according to how deep into the layer's structure one wants to venture. This makes the "web" fully adaptable to individuals' interests and emotive states. But also, it enables exploration through the use of different resolution levels, bot...

in this paper, the electronic eigenstates and energy spectra of single and two-interacting electrons confined in a concentric double quantum rings with a perpendicular magnetic field in the presence of         on-center donor and acceptor impurities are calculated using the exact diagonalization method. for a single electron case, the binding energy of on-center donor and acceptor impurities ar...

lack of trust is one of the key bottle necks in e-commerce development. nowadays many advanced technologies are trying to address the trust issues in e-commerce. one among them suggests using suitable user interfaces. this paper investigates the functionality and capabilities of 3d graphical user interfaces in regard to trust building in the customers of next generation of b2c e-commerce websit...