In this paper we present the results of a dosimetric evaluation of a 2D ionization chamber array with the objective of its implementation for quality assurance in clinical routine. The pixel ionization chamber MatriXX (Scanditronix Wellhofer, Germany) consists of 32x32 chambers with a distance of 7.6 mm between chamber centres. The effective depth of measurement under the surface of the detecto...

Pancreatic cancer is a devastating disease with poor survival outcomes. Recent studies have shown that the addition of radiotherapy to chemotherapy in the setting of locally advanced pancreatic cancer did not improve overall survival outcome. These studies commonly utilize conventional radiotherapy treatment fractionation and technique (typically 3-D conformal radiotherapy or intensity modulate...

Background: External beam radiotherapy (EBRT) is mainstay of treatment in patients with locally advanced cervical carcinoma (LACC). Three dimensional conformal radiotherapy (3DCRT) and intensity modulated radiotherapy (IMRT) are mainly used in EBRT. However which one is superior is still controversial. Materials and Methods: Forty patients of LACC treated with IMRT were selected for this study....

Radiochromic film has become an important tool to verify dose distributions in highly conformal radiation therapy such as IMRT. Recently, a new generation of these films, EBT3, has become available. EBT3 has the same composition and thickness of the sensitive layer of the previous EBT2 films, but its symmetric layer configuration allows the user to eliminate side orientation dependence, which i...

Background: Intensity Modulated Radiotherapy (IMRT) can improve radiotherapy (RT) results by improving healthy tissue sparing. Additionally, IMRT provides more consistent dose deliveries and suppresses secondary tumor formation. RT is a principal treatment in breast cancer (BC). Aim: To evaluate the outcome of the Radiotherapy Plans (RTP) that use IMRT technique to left breast and other organs,...

AIM OF THE STUDY Helical tomotherapy is one of the methods of radiotherapy. This method enables treatment implementation for a wide spectrum of clinical cases. The vast array of therapeutic uses of helical tomotherapy results directly from the method of dose delivery, which is significantly different from the classic method developed for conventional linear accelerators. The paper discusses the...

New advances in radiation therapy for children allow increased conformability and reduced doses to non-target tissues. We report our experience in treating a 4-year-old child with craniospinal tomotherapy after surgery of the primary tumor, a supratentorial primitive neuroectodermal tumor. The tomotherapy plan was compared with conventional craniospinal irradiation, 3D conformal radiation thera...

This retrospective study was performed to evaluate and compare gastrointestinal (GI) toxicities caused by conventional radiotherapy (cRT) and intensity modulated radiotherapy (IMRT) in 136 cancer patients treated with pelvic radiotherapy (RT) with moderate radiation dose in a single institution. A matched-pair analysis of the two groups was performed; each group included 68 patients. Convention...

Introduction: GRID therapy is a treatment modality in which a high dose of radiation in a single fraction is given to the tumor. This technique previously was used to treat bulky tumors with orthovoltage beams. Recently, studies have been conducted to suggest that GRID therapy with megavoltage photons can be useful in palliative treatments. On the other hand, there has always ...

AIMS AND BACKGROUND We compared conformal, intensity-modulated radiotherapy (IMRT) and intensity-modulated arc therapy (IMAT) in early stage glottic cancer in terms of dosimetric features as target coverage, dose to the organs at risk and total treatment time. METHODS AND MATERIALS Five consecutive T1 glottic squamous cell carcinoma patients were selected for the study. Three-dimensional conf...