ISSN: 1538-4047 (Print) 1555-8576 (Online) Journal homepage: http://www.tandfonline.com/loi/kcbt20 Inhibiting phosphoinositide 3-kinases Yardena Samuels, Jiuxiang Zhu & Christoph Lengauer To cite this article: Yardena Samuels, Jiuxiang Zhu & Christoph Lengauer (2005) Inhibiting phosphoinositide 3-kinases, Cancer Biology & Therapy, 4:5, 546-547, DOI: 10.4161/cbt.4.5.1669 To link to this article:...

produced by the corpus luteum of pregnancy, and later by the placenta, are responsible for this effect. Similarly, the administration of the naturally occurring steroids, such as estradiol and progesterone can inhibit ovulation. However, these steroids are unsatis factory for clinical use as they are not regularly effective and secondly, the parenteral administration of progesterone is painful....

The satellite TV industry relies heavily on the use of smart card technology at the very heart of broadcasted services that are protected by legacy conditional access systems. The process of Satellite TV signal protection is distributed amongst a number of system components, e.g. smart cards, receivers, Conditional Access Modules (CAM) and the content provider. However, the introduction of “Ope...

It has been known for many years that the immune system can actively respond to (pre)neoplastic cells and prevent oncogenesis (a concept known as cancer immunosurveillance). However, in most cases, antitumor immune responses are inefficient and neoplasms are allowed to establish. Indeed, effector T cells often infiltrate developing malignant lesions and may significantly influence the prognosis...

We report the use of atomically thin layers of graphene as a protective coating that inhibits corrosion of underlying metals. Here, we employ electrochemical methods to study the corrosion inhibition of copper and nickel by either growing graphene on these metals, or by mechanically transferring multilayer graphene onto them. Cyclic voltammetry measurements reveal that the graphene coating effe...

Evidence is reviewed indicating that output interference—the deleterious effects of recall of some information on information recalled later—occurs both in primary and secondary memory. It appears that output interference provides at least a partial account for the disparity between information available in memory and its accessibility at recall. It is argued that consideration of...

It is widely believed that whether we are talking about command and control teams, joint task forces or coalition forces, the “organization” must be adaptive. Unanticipated changes in mission, rapidly evolving technologies, intelligent and changing opponents, and so forth have created a need to create forces that can respond rapidly, accurately and can readily adapt to new situations. Over the ...

abstract in order to determine efficacy of some registered graminicides in control of resistant and susceptible ryegrass biotypes, two greenhouse trials were conducted at weed research department of iranian plant protection research institute during 2007. experimental design was completely randomized design with eight replications. the susceptible and resistant biotypes were treated by 19 herbi...

background: osteosarcoma is a malignant tumor with high mortality but effective therapy has not yet been developed. berberine, an isoquinoline alkaloid component in several chinese herbs including huanglian, has been shown to induce growth inhibition and the apoptosis of certain cancer cells. the aim of this study was to determine the role of berberine on human osteosarcoma cell lines u2os and ...