نتایج جستجو برای: influenza a virus

تعداد نتایج: 13592096  

Journal: :novelty in biomedicine 0
somaie tavakoli biochemistry department, faculty of basic sciences, payame-noor university mojgan bandehpour biotechnology department,school of medicine, shahid beheshti university of medical sciences zeinab soleimanifar department of biotechnology, school of medicine, shahid beheshti university of medical sciences, tehran, iran mehdi goudarzi department of microbiology, school of medicine, shahid beheshti university of medical sciences, tehran, iran bahram kazemi biotechnology department,school of medicine, shahid beheshti university of medical sciences

background: influenza virus is the major cause of lower respiratory tract illnesses on the worldwide. vaccination can be an effective tool to prevent its outbreak. highly conserved viral nucleoprotein is an effective vaccine candidate to provide heterosubtypic immunity, offering resistance against various influenza virus strains. m aterials and methods: in present research np gene was inserted ...

Journal: :jundishapur journal of microbiology 0
seyedeh zahra mosavi razi vaccine and serum research institute, karaj, ir iran shahla shahsavandi razi vaccine and serum research institute, karaj, ir iran; razi vaccine and serum research institute, karaj, ir iran. tel: +98-2634570038 mohammad majid ebrahimi razi vaccine and serum research institute, karaj, ir iran ali reza hatami razi vaccine and serum research institute, karaj, ir iran kaveh sadeghi razi vaccine and serum research institute, karaj, ir iran hassan shahivandi social security hospital, khorram abad, ir iran

conclusions taken together, these data reveal that cellular protease of chicken liver cells allows the replication of high yields of h9n2 virus in the absence of trypsin and also cell death in the infected cells is due to necrosis. results the degree of viability was significantly reduced in infected hepatoma cells. observations of caspase activation and cell dna laddering in infected cells wer...

اکبری, عطیه, توکلی, رضوان, جلیلی, ندا, طاهری, نجمه, فتوحی, فاطمه, فرهمند, بهرخ,

Background and purpose: Influenza virus is one of the most important respiratory infectious agents. Viral antigenic variations are major problems for vaccine production process. At present, many researches have focused on conserved domains of influenza virus antigenic peptides for subunit vaccine development. Hemagglutinin small subunit (HA2) and the 23 amino acid extracellular N-terminal domai...

Journal: :Journal of virology 2001
J S Peiris Y Guan D Markwell P Ghose R G Webster K F Shortridge

Pigs are permissive to both human and avian influenza viruses and have been proposed to be an intermediate host for the genesis of pandemic influenza viruses through reassortment or adaptation of avian viruses. Prospective virological surveillance carried out between March 1998 and June 2000 in Hong Kong, Special Administrative Region, People's Republic of China, on pigs imported from southeast...

Journal: :archives of medical laboratory sciences 0
maedeh bahreinian farida behzadian fatemeh fotouhi

background: influenza viruses are a significant cause of morbidity and mortality. the influenza virus pandemics, 1918, 1977, and especially the most recent one, a/h1n1/2009, made evident the need for generating recombinant influenza h1n1 antigens which are essential to develop both basic and applied research programs. among influenza virus proteins, haemagglutinin (ha) is a major surface antige...

Journal: :Journal of virology 1996
Y Guan K F Shortridge S Krauss P H Li Y Kawaoka R G Webster

Avian influenza A viruses from Asia are recognized as the source of genes that reassorted with human viral genes to generate the Asian/57 (H2N2) and Hong Kong/68 (H3N2) pandemic strains earlier in this century. Here we report the genetic analysis of avian influenza A H1N1 viruses recently isolated from pigs in southern China, a host suspected to generate new pandemic strains through gene reasso...

Journal: :iranian biomedical journal 0
معصومه توسطی خیری masoumeh t. kheiri susan gould-fogerite eleonora feketeova raphael j. mannino zheng wang zheng wang raphael j. mannino eleonora feketeova susan gould-fogerite

high morbidity and mortality of influenza virus infection makes it an important disease world-wide. mouse is a very well-studied animal model for this disease with similar manifestation to human disease. it would be desirable to induce mucosal as well as circulating immune responses to obtain protection from infection and to decrease the spread of the virus. cell mediated immunity (proliferativ...

Journal: :modares journal of medical sciences: pathobiology 2010
abbas jamali farzaneh sabahi taravat bamdad hamaid reza hashemi fereidoun mahboudi

objective: the use of bacterial plasmids carrying specific genes of pathogens as genetic vaccines is a relatively new technique for induction of cellular immune responses against microbial pathogens. mechanisms of production of specific immune responses against these vaccines are not still completely understood. therefore, it is necessary to examine various routes of inoculation to find the bes...

Akbari, H, Amiri, B, Dadras, M, Darvishi, S, Erfani, H, Gouya, MM, Hemati, P, Mokhtari Azad , T, Moradi, GH, Rahmani, KH, Rezaei, F, Soltani, J, Soroush, M,

Background and Objectives: Iran, like most other countries in the world, is always threatened with global epidemics and pandemics of influenza. The purpose of this study was to review the influenza surveillance system in Iran.   Methods: Data of this study were obtained from the surveillance system of the Center for Communicable Disease Control, the review of records, documents, books and pub...

Journal: Vaccine Research 2014
Abbas Jamali, Abdolhossein Amini Rissehei, Asghar Abdoli, Hoorieh Soleimanjahi, Masoumeh Tavassoti Kheiri, Nabiollah Namvar Asl, Peyvand Biglari, Shima Gholami,

  Introduction: The preparation of seasonal influenza virus vaccines and especially its large-scale production requirement after the emergence or reemergence of a pandemic will need an alternative host cell system due to current suboptimal methods and the insufficiency of embryonated chicken eggs needed for producing them. In response to the vital and increasing demand for alternative means for ...

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