نتایج جستجو برای: inflammatory hyperpigmentation
تعداد نتایج: 263385 فیلتر نتایج به سال:
Background. Patients on chronic minocycline suppression for orthopedic infections at a single institution were studied for development of minocycline-induced cutaneous hyperpigmentation and analysis of risk factors. Methods. This is a retrospective cohort study of Mayo Clinic patients with hardware or non-hardware associated chronic orthopedic infections treated with long termminocycline suppre...
Melanin is a pigment that contributes to our skin color. Hyperpigmentation where melanin is produced in excess quantity can cause significant esthetic problem. Facial aesthetics is affected by smile line. Gingiva is an integral component of facial esthetics. Hyperpigmentation in gingiva affects facial esthetics. Various surgical modalities have been employed to correct hyperpigmentation. But, r...
There are numerous common skin disorders involving hyperpigmentation, including solar lentigines, postinflammatory hyperpigmentation, melasma, freckles, and dyschromia from photoaging. While these conditions are of an aesthetic nature, there is great interest in newer, safer, and more effective treatment modalities. Topical hydroquinone (HQ) has been the gold standard of skin lighteners for man...
BACKGROUND Cutaneous hyperpigmentation is an often overlooked clinical sign in megaloblastic anemia (MA) which has been sporadically reported in the literature. METHODS We describe the bone marrow (BM) changes and clinicolaboratory characteristics of 25 of 198 adult cases (>16 years) with cutaneous hyperpigmentation who underwent BM evaluation for cytopenia (s). RESULTS Twenty-one of 25 cas...
INTRODUCTION Pityriasis rosea is a self-limited inflammatory condition of the skin that mostly affects healthy children and adolescents. Atypical cases of Pityriasis rosea are fairly common and less readily recognized than typical eruptions, and may pose a diagnostic challenge. CASE PRESENTATION We report the case of a 12-year-old black child that developed an intense pruritic papular eruptio...
INTRODUCTION Systemic sclerosis is a systemic connective tissue disease with variable cutaneous presentations. Although pigmentary disturbances have been described in systemic sclerosis, a reticulate hyperpigmentation has only been reported in one case of systemic sclerosis to date. CASE PRESENTATION We describe a previously healthy 51-year-old Thai woman who presented with a reticulate hyper...
We previously reported that three point mutations in SASH1 and mutated SASH1 promote melanocyte migration in dyschromatosis universalis hereditaria (DUH) and a novel p53/POMC/Gαs/SASH1 autoregulatory positive feedback loop is regulated by SASH1 mutations to induce pathological hyperpigmentation phenotype. However, the underlying mechanism of molecular regulation to cause this hyperpigmentation ...
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