A novel isolate of infectious bursal disease virus (IBDV) was designated GX-NN-L. The GX-NN-L IBDV was a very virulent infectious bursal disease virus (vvIBDV) isolated from broiler flocks in Guangxi province, China, in 2011. The GX-NN-L IBDV caused high mortality, immunosuppression, low weight gain, and bursal atrophy in commercial broilers. Here, we report the complete genome sequence of the ...

Chickens susceptible to infectious bursal disease (IBD) became viremic for only a transient period when inoculated with two different strains of infectious bursal disease virus (IBDV). The virus was not isolated from tissues beyond 10 days postinoculation. There was no apparent spread of IBDV to susceptible contact chickens placed with infected groups 16, 30, 42, and 52 days postinoculation. At...

Here we report on vaccination approaches against infectious bursal disease (IBD) of poultry that were performed with complete yeast of the species Kluyveromyces lactis (K. lactis). Employing a genetic system that enables the rapid production of stably transfected recombinant K. lactis, we generated yeast strains that expressed defined quantities of the virus capsid forming protein VP2 of infect...

Newcastle disease (ND) and infectious bursal (IBD) are both one of the most economically important diseases, which cause high infection rate mortality chickens restrict development poultry industry. Currently, vaccination is effective method to prevent ND IBD. In this study, biological adjuvant bivalent vaccine (rClone30-VP2L-chGM-CSF) was developed for preventing Furthermore, immune protective...

Infectious bursal disease (IBD), commonly known as “Gumboro Disease is an infectious viral disease of chickens inducing severe immunosuppression. In Pakistan, imported vaccine is used to prevent the disease but there have been outbreaks even in vaccinated flocks. This indicates that there is variation among the locally prevalent viral strains and commercially available vaccine strain. In presen...

This study evaluated the effects of live yeast (LY, Saccharomyces cerevisiae) on growth performance, nutrient digestibility, immune function, antioxidant status and intestinal morphology broilers. A total 224, 1 day-old broilers were assigned 4 treatments (7 replications, 8 chicks each) fed a basal diet control group (CTR); antibiotic (CTC) diets with chlortetracycline at 75 mg/kg; LY-1 LY-2 gr...