erpetic burn wound infection was initially described by Scott and colleagues1 over four decades ago. A 2-year-old girl burned her finger on a cigarette and the area was kissed by her mother, who had a history of orolabial herpes. Although the burn appeared to heal, it became blistered 2 days after the injury, and vesicular lesions developed along the hand and arm, from which herpes simplex viru...

Gram-negative infections predominate in burn surgery. Until recently, Achromobacter species were described as sepsis-causing bacteria in immunocompromised patients only. Severe infections associated with Achromobacter species in burn patients have been rarely reported. We retrospectively analyzed all burn patients in our database, who were treated at the Intensive Care Burn Unit (ICBU) of the C...

Objectives:Staphylococcus aureus infections in burn patients can lead to serious complications and death. The frequency of S. aureus infection is high in low- and middle-income countries presumably due to limited resources, misuse of antibiotics and poor infection control. The objective of the present study was to apply population genomics to precisely define, for the first time, the transmissi...

Sepsis has recently been defined as "life-threatening organ dysfunction caused by a dysregulated host response to infection". A great amount of effort has been made to develop early treatments for sepsis through the Surviving Sepsis Campaign. There are similar but slightly different recommendations for the treatment of sepsis in the pediatric population. These international efforts have led to ...

Background:Infection prevention and control is critical component of patient safety, as hospital acquired infection are the most common complication affecting hospitalized patients. The aim of this study was to evaluate effect of implementing nursing guidelines on nurse's knowledge and patient's safety regarding nosocomial infection control measures in burn unit. Methods: A quasi-experimental d...

Burns are considered one of the most common and shocking forms of trauma. Patients with serious thermal or electrical injury necessitate immediate specialized care to minimize morbidity and mortality. Electrical burns and burn injuries caused by fire, hot liquids, and contact with hot surfaces, have been recognized as a significant and major public health problem in most developing countries. B...

Modern burn care has led to unprecedented survival rates in burn patients whose injuries were fatal a few decades ago. Along with improved survival, new challenges have emerged in the management of burn patients. Infections top the list of the most common complication after burns, and sepsis is the leading cause of death in both adult and pediatric burn patients. The diagnosis and management of...

INTRODUCTION Burn injury and its subsequent multisystem effects are commonly encountered by acute care practitioners. Resuscitation is the major component of initial burn care and must be managed to restore and preserve remote organ function. Later complications of burn injury are dominated by infection. Burn centers are often called to manage soft tissue problems outside thermal injury includi...

BACKGROUND Nanoemulsions are broadly antimicrobial oil-in-water emulsions containing nanometer-sized droplets stabilized with surfactants. We hypothesize that topical application of a nanoemulsion compound (NB-201) can attenuate burn wound infection. In addition to reducing infection, nanoemulsion therapy may modulate dermal inflammatory signaling and thereby lessen inflammation following therm...

BACKGROUND Astragalus polysaccharides (APS) isolated from one of the Chinese herbs, Astragalus mongholicus, are known to have a variety of immunomodulatory activities. However, it is not yet clear whether APS can exert an effect on the immune functions of regulatory T cells (Tregs). This study was carried out to investigate the effect of APS on the immune function of peripheral blood Tregs in p...