A study of 887 consecutively born immigrant Greek and 220 Anglo-Saxon Australian infants has shown that serum bilirubin concentrations are influenced by these factors: breast feeding, delivery with forceps, gestation, birthweight, sex of the infant, presence of hypoxia, presence of blood group incompatibility, a positive direct Coombs's test, maternal sepis, and administration to the mother of ...

Isolated ACTH deficiency (IAD) is a rare cause of neonatal cholestasis and hypoglycaemia. This diagnosis has a 20% mortality potential if unrecognised. We describe a case of an infant presenting with cholestatic jaundice and hypoglycaemia. The patient had laboratory findings suggestive of IAD, which was later confirmed with molecular genetic testing. One of the mutations this patient had is a n...

Hargreaves, T. (1973). Archives of Disease in Childhood, 48, 446. Effect of fatty acids on bilirubin conjugation. The effect of fatty acids on bilirubin conjugation has been studied. Unsaturated fatty acids containing 18 to 20 carbon atoms decreased the rate of conjugation in rat liver slices and microsomes, probably by inhibiting glucuronyl transferase. Since fatty acids may be an important so...

A 20-day-old girl was referred to our department for cutaneous lesions that appeared 1 week earlier and were not associated with any other symptoms (Figures 1 and 2). On the third day of life, the infant had presented jaundice and had been treated by phototherapy, which led to resolution of the symptoms within 48 hours. As relevant family history, the mother was currently being assessed for joi...

ABO hemolytic disease is the most common blood group incompatible hemolytic processes of the newborn period and is the major cause of neonatal jaundice attributed to maternal infant blood incompatibility. This was a prospective cohort study which included 50 consecutive term appropriate for gestational age babies with blood group either A, B or AB, born to O +ve mothers as the study group and a...

Jaundice is a yellow discoloration of the skin and whites of the eyes that is often seen in newborns. Newborn jaundice can be analyzed by scrutinizing the infant and examining blood levels of bilirubin. Infants with high blood levels of bilirubin called hyperbilirubinaemia, evolve the yellow color when bilirubin acquires in the skin. The major symptom of jaundice is yellow coloring of the skin ...

CONTEXT The pancreas is an unusual site for a hemangioma in an infant. A child with obstructive jaundice caused by a pancreatic hemangioma is presented and management strategies for this benign tumor are discussed. CASE REPORT A 5-month-old girl presented with a 2-week history of jaundice, pale stools and dark urine. Liver function tests confirmed obstructive jaundice. An abdominal ultrasound...

BACKGROUND Neonatal jaundice, especially breast feeding jaundice is the most common cause of neonatal re-admission within the first month of life. Good maternal support and closed follow-up of newborn infants can promote successful breast feeding without causing any complications. OBJECTIVE To determine the rate of significant weight loss and hypernatremia in infants with breast feeding jaund...

Sudden infant death syndrome (SIDS) is a common cause of mortality belowone year, and its causes remain unknown. However, simple protective practices in infantsleep sleep environment can dramatically reduce incidence. Aim: Assess themothers’ knowledge for the prevention SIDS. Method:Descriptiveresearch was conducted postnatal department at general hospital Kafrelsheikh city,Egypt, on 180 newly ...

The conception of the pathological entity of the three manifestations of haemolytic disease of the newborn: hydrops foetalis, icterus gravis and congenital haemolytic anaemia has been confirmed by the discovery of the Rhesus factor. Moreover, this discovery has allowed us finally to abandon any sharp clinical distinction between the two latter forms of the disease. This is in accord with the fa...