نتایج جستجو برای: indolizines
تعداد نتایج: 119 فیلتر نتایج به سال:
BACKGROUND/AIM The potential of indolizine derivatives as anticancer agents has been shown through recent studies. Herein, we present our experimental results, showing that pyrido[2,3-b]indolizine derivatives are effective against colorectal cancer (CRC) cell lines. MATERIALS AND METHODS Several pyrido[2,3-b]indolizine derivatives were synthesized and their anticancer potential was evaluated ...
New compounds having two indolizine nuclei in a molecule were prepared in low to moderate yields from the reactions of potassium 2-indolizinethiolates with 1,omega-dihalides such as 1,2-diiodoethane, 1,3-dibromopropane, 1,4-dibromobutane, alpha,alpha'-dichloro-o-xylene, and alpha,alpha'-dichloro-p-xylene. Most of the products had the conformation in which the two indolizine rings in the molecul...
C−H bond formylation is the most immediate way to incorporate versatile formyl group into (hetero)aromatics. However, type of reagents and severe conditions involved in classical methods often curtail their application, especially presence other functional groups. Herein, we present Eschenmoser's salt, a commercially available (dimethylamino)methylating chemical, as useful reagent for indolizin...
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