Nicotine dependence is common in people with mood disorders; however the operative pathways are not well understood. This paper reviews the contribution of inflammation and oxidative stress pathways to the co-association of depressive disorder and nicotine dependence, including increased levels of pro-inflammatory cytokines, increased acute phase proteins, decreased levels of antioxidants and i...

Acute morphine withdrawal is considered to be the physical manifestation of dependence, emerging when morphine administration is stopped or after the administration of an opiate antagonist, such as naloxone. Gabapentin, which is an antiepileptic, agent, enhances the analgesic effect of morphine in healthy volunteers, but its effect on morphine dependence and withdrawal signs has not determined ...

Hyperhidrosis is a disorder of excessive sweating beyond what is physiologically necessary for thermoregulation. Primary hyperhidrosis is localized; it can affect the axillae, palms, soles, face, and other areas and is idiopathic. The prevalence of hyperhidrosis in the United States is estimated to be 2.8% of the population, with about one-half (1.4%) of these individuals having the axillary fo...

chirurgie) advises the employment of these means to rid the system of poison in puerperal septiccemia. Of course, the early treatment of this disease, if the case is seen in time, is, first, by asepsis and antisepsis by means of uterine irrigation, etc. ; and, secondly, by the use of alcohol and every means to prevent the poison from overpowering the organism. But, if the morbid germs and their...

we have first to look at its effects in small doses and then in larger and constant doses. I will not enter into arguments about the harm, misery and crime it is responsible for, suffice it to say that it can save as well as destroy. Alcohol in moderate doses stimulates the brains, the respiratory and cardiac nerves, and produces capillary dilatation, diaphoresis, and a sensation of warmth, but...

OBJECTIVES This case report aims to help healthcare providers and methadone clinic patients to recognize one of the less recognized adverse effects of methadone, hyperhidrosis, and to suggest oxybutynin as a possible solution. METHODS A 35-year-old man on methadone maintenance therapy presented with excessive sweating, which began promptly after methadone was introduced. Urine toxicology was ...

Vertigo is a sensation of movement when no movement is actually occurring. It is often accompanied by visceral autonomic symptoms including pallor, diaphoresis, nausea, and vomiting. Vertigo is similar to motion sickness in that both may be caused by vestibular stimulation that does not match an internal model of expected environmental stimuli. Indeed, a functioning vestibular system is necessa...

Two-terminal integrated circuit temperature transducers (Analog Devices' AD 590) were used to fabricate skin and rectal probes for the monitoring of mean body temperature. They are inexpensive, robust, easily constructed and of low mass. The skin sensor system described is capable of being solidly attached regardless of the body contour such that it remains integral throughout profuse sweating ...