OBJECTIVE Many surgeons advocate for watertight dural reconstruction after posterior fossa surgery given the significant risk of cerebrospinal fluid (CSF) leak. Little evidence exists for posterior fossa dural reconstruction utilizing monolayer collagen matrix onlay graft in a non-watertight fashion. Our objective was to report the results of using collagen matrix in a non-watertight fashion fo...

Stoma reversal is a commonly performed procedure. Surgical site infection (SSI) is one of the most common complications following stoma reversal with reported incidence of up to 41% [1,2]. Surgical site infection leads to increased medical cost, requires additional wound care and extra medications. It might also prolong length of hospital stay and adversely affect quality of life [3,4]. Followi...

Background Acute postoperative pain is induced by most incisional surgeries and usually resolves with wound repair. However, many patients experience moderate to severe pain despite receiving currently available postoperative pain relief. Accumulating evidence suggests that inflammatory cells, neutrophils, and macrophages infiltrating the wound site contribute to the acute inflammation, pain, a...

Data regarding the outcomes of peritoneal dialysis (PD) patients undergoing nephrectomy are limited. In the 20-year retrospective study reported here, we included patients who underwent nephrectomy and then subsequently started PD within 1 year (group A) and those who underwent nephrectomy while already on PD (group B). We examined mechanical complications including incisional hernia, peritonea...

Despite advances in surgical technique and prosthetic technologies, the risks for recurrence and infection are high following the repair of incisional ventral hernias. High-quality data suggest that all ventral hernia repairs should be reinforced with prosthetic repair materials. The current standard for reinforced hernia repair is synthetic mesh, which can reduce the risk for recurrence in man...

285 Received August 31, 2011; revision accepted for publication November 3, 2011. doi: 10.1620/tjem.225.285 Correspondence: Xiaoyu Yan, M.D., Ph.D., Department of Orthopedic Surgery, Shanghai Sixth People’s Hospital, Shanghai Jiao Tong University, No. 600, Yishan Road, Shanghai 200233, P.R. China. e-mail: yan [email protected] Extracorporeal Shock Wave Treatment Improves Incisional Wound Healing in...

Propolis is a resinous, sticky substance that bees collect from conifer buds and use to repair cracks in their hives. Propolis was used in folk medicine as early as 300 BC as an anti-inflammatory drug and wound healing agent. We studied the effect of Propolis on wound healing in albino rats. Twenty male albino rats had a linear 3 cm incision made over skin of back. The animals were randomly div...

Pain hypersensitivity at the site of inflammation as a result of chronic immune diseases, pathogenic infection, and tissue injury is a common medical condition. However, the specific contributions of the innate and adaptive immune system to the generation of pain during inflammation have not been systematically elucidated. We therefore set out to characterize the cellular and molecular immune r...

This study evaluates the sustained analgesic effect of ketorolac-eluting thermosensitive biodegradable hydrogel in the plantar incisional pain model of the rat hind-paw. A ketorolac-embedded 2, 2'-Bis (2-oxazolin) (BOX) linking methoxy-poly(ethylene glycol) and poly(lactide-co-glycolide) (mPEG-PLGA) diblock copolymer (BOX copolymer) was synthesized as keto-hydrogel based on optimal sol-gel phas...