Mechanistic studies on demineralization-remineralization play a critical role in investigating caries pathogenicity, testing effects of new caries prevention methods, and developing new caries-preventing products. Simulating the cariogenic challenges in the mouth, various demineralization-remineralization models have been used for cariology research. This review aimed to provide an overview of ...

background and objectives: dental caries is still remained as a major health problem. this problem has created a new interest to search for new antimicrobial agents from various sources including medicinal plants. since limited data is available so far regarding the antibacterial effect of coriandrum sativum seed and dentol drop against streptococcus mutans, this study aims to assess this activ...

A variety of antibiotic and chemotherapeutic agents were tested for their ability to inhibit the development of dental caries in Sprague-Dawley rats receiving the drugs in a coarse-particle sucrose-containing diet. Drugs which inhibit gram-positive microorganisms were effective inhibitors of caries, whereas agents which are active solely against gram-negative bacteria did not inhibit caries dev...

introduction: it was to compare the efficacy of semiannually fluoride varnish application versus pit and fissure sealant to reduce occlusal caries incidence. materials and methods: a randomized parallel designed study was conducted with 352 child-ren aged 6-7 years. participants were allocated into biannual application of varnish (n=179) (naf 5 %( durafluor, dentsply®, latin america) or resin-b...

Objective: To evaluate TIF4 preventive and therapeutic use in caries erosive lesions. Material Methods: Searches were performed six databases. Studies evaluating TiF4 vitro, situ, vivo lesions included imported into VantagePoint™ (VP). Data about publication year, authors, country, journal, study design, outcomes, vehicles, application intervention time, cariogenic challenge, cycles, effects (p...