backround laryngopharyngeal reflux (lpr) is the backflow of stomach contents above upper esophageal sphincter, into the pharynx, larynx, and upper aerodigestive system. objectives in this study, effects of omeprazole over voice quality in muscle tension dysphonia with laryngopharyngeal reflux was ınvestigated. patients and methods nine patients, 7 males and 2 females, aged between 27-43 (mean a...

design of selective cyclooxygenase-2 (cox-2) inhibitors is still a challenging task because of active site similarities between cox isoenzymes. to help with this issue, we tried to generate a 3d-qsar (3 dimensional quantitative structure activity relationship) model that might reflect the essential features of cox-2 active sites. compounds in a series of resveratrol derivatives inhibitors with ...

background: acid phosphatase (acp) is suggested to be one of the virulence factors in leishmania and a correlation has been reported between leishmanial acid phosphatase (acp) activity and the severity of the disease in all types of leishmaniasis including zoonotic cutaneous leishmaniasis (zcl), which is a polymorphic disease.   objective : characterization of leishmania and its correlation wit...

the corrosion inhibition characteristics of two synthesized schiff bases, namely n, n´-bis(2-hydroxy-6-nitrobenzaldehyde) benzidine  and n, n´-bis(salysylaldehyde) benzidine, on the mild steel corrosion in 2.0 m hydrochloric acid have been investigated by weight loss, potentiodynamic polarization and electrochemical impedance spectroscopy techniques. these studies were carried out at different ...

non-steroidal anti-inflammatory drugs (nsaids) are the competitive inhibitors of cyclooxygenase (cox), the enzyme which mediates the bioconversion of arachidonic acid to inflammatory prostaglandins (pgs). their use is associated with the side effects such as gastrointestinal and renal toxicity. the therapeutic anti-inflammatory action of nsaids is produced by the inhibition of cox-2, while the ...

In this investigation, attempts were directed to study the inhibitive effects of nitrite and phosphate base inhibitors for the carbon steel alloy samples, which are used in an acid gas treatment process (The SULFIRAN® solution), in Fe-EDTA solution. Electrochemical techniques, i.e. polarization curves and electrochemical impedance spectroscopy (EIS), were used to evaluate the inhibition efficie...

the date palm fruit stalk borer is one of the most important pests of date palm in the world. biochemical properties of digestive proteases in oryctes elegans prell larvae were investigated in this research and optimal total proteolytic and trypsin activities were obtained at ph 9.0 and 11.0, respectively. activity staining of protease on sds-page showed one isoform. also, zymogram pattern of t...