نتایج جستجو برای: immunotoxicity
تعداد نتایج: 652 فیلتر نتایج به سال:
A systematic literature review has been performed on the toxicological profiles of pyrethroid common metabolites 3-phenoxybenzoic acid (PBA), 3-(4’-hydroxyphenoxy)benzoic (PBA(OH)) and 3-phenoxybenzaldehyde (PBAld). Following definition appropriate search strings 1031 publications were screened by abstract, title keywords followed a screening full texts 82 publications. From these 20 could be i...
An entire cycle of preclinical studies 4-[(3-ethoxy-3-oxopropanoyl)amino]benzoic acid (etmaben) exhibiting cardiotropic action was carried out. Its potential mechanism and pharmacological effects, general toxic effects in acute chronic experiments, specific types toxicity (allergenicity, immunotoxicity, reproductive toxicity, mutagenicity), pharmacokinetics were studied. The drug found to have ...
Targeting immune inhibitory receptors has brought excitement, innovation and hope to cancer patients. Our recent work revealed the immunological effects of blocking the CTLA4 and PD-1 immune checkpoints on T cell receptor usage among peripheral blood cells, and further uncovers how the expansion of the T cell repertoire matches the immunotoxicity profile of the therapy.
Research over the past three decades has shown that the mammalian immune system can be altered by the occupational exposure of asbestos. Early clinical studies generally focused on systemic observations of immune alteration such as the number and function of peripheral lymphocytes and monocytes. More recently as the regulatory influence of local immunity in health and disease becomes more defin...
PD-L1 aptamer-based spherical nucleic acids (SNAs) were designed that consist of oxaliplatin (OXA) encapsulated in a metal–organic framework (MOF) nanoparticle core and dense shell aptamer (denoted as M@O-A), reported by Zhengyu Jin, Jie Tian, Yang Du, co-workers their Research Article (e202214750). Upon light irradiation, the versatile M@O-A allows for robust photo-immunotherapy against cancer...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید