نتایج جستجو برای: immunosuppressive medications
تعداد نتایج: 65938 فیلتر نتایج به سال:
Highly active antiretroviral therapy has dramatically altered the treatment and life expectancy of individuals who are infected with HIV. More than 20 antiretroviral drugs and drug combinations now are available in the United States. Nephrologists need to have an understanding of the pharmacokinetics of antiretroviral medications and the proper dosing of these medications in patients with impai...
Neuromyelitis optica (NMO) is an autoimmune demyelinating disease preferentially targeting the optic nerves and spinal cord. Once regarded as a variant of multiple sclerosis (MS), NMO is now recognized to be a different disease with unique pathology and immunopathogenesis that does not respond to traditional MS immunomodulators such as interferons. Preventive therapy in NMO has focused on a ran...
Transplant medicine has seen many innovations over past decades and continues to evolve into the 21st century. Newer immunosuppressive strategies in renal transplantation are associated with better patient and graft survival rates; however, the adverse toxicities and long-term side effects associated with these agents present a number of challenges. Certain immunosuppressants are commonly used ...
Grapefruit is a healthy addition to a well-balanced diet. However, the fruit has been shown to affect the metabolism of many medications, increasing the risk of toxicity and adverse effects. Characteristics of oral medications that may interact with grapefruit include extensive metabolism through the intestinal cytochrome P450 3A4 system, low bioavailability, and a narrow therapeutic index. Pro...
Abstract Background and Aims One of the major barriers for long-term transplant outcomes in kidney recipients is medication non-adherence, which a risk factor de novo donor-specific antibody development leading to antibody-mediated rejection graft loss. Identifying non-adherent patients first step minimizing complications non-adherence. However, date, there no validated Japanese self-report ins...
hypertension after pediatric renal transplant is a common and important risk factor for graft loss and patient survival. the mechanism of post kidney transplant hypertension is complex and multifactorial. control of blood pressure in renal transplant patients is important but often times blood pressures remain uncontrolled. the management of hypertension and obesity in pediatric kidney transpla...
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