Myopodin is an actin-binding protein that shuttles between the nucleus and the cytoplasm. After identifying an enriched CpG island encompassing the transcription site of myopodin, we aimed at evaluating the potential relevance of myopodin methylation in bladder cancer. The epigenetic silencing of myopodin by hypermethylation was tested in bladder cancer cells (n=12) before and after azacytidine...

genitourinary tuberculosis (gutb) is difficult to diagnose in the earlier stage owing to the non-specific symptoms. usually, renal tuberculous involvement is unilateral and the imaging finding is renal calcification, but associated calcifications of bilateral ureter and bladder are rare. we report a 66-year-old man who presented with diffuse calcification of the urinary system (including bilate...

PURPOSE Polyamines are important regulators of cell growth and death. The polyamine modulated factor-1 (PMF-1) is involved in polyamine homeostasis. After identifying an enriched CpG island encompassing the PMF1 promoter, we aimed at evaluating the clinical relevance of PMF1 methylation in bladder cancer. EXPERIMENTAL DESIGN The epigenetic silencing of PMF1 by hypermethylation was tested in b...

We report a primary choriocarcinoma of the urinary bladder in a 63-year-old man who presented with painless hematuria. He was diagnosed as having an invasive carcinoma and underwent a total cystectomy. The tumor was diffusely hemorrhagic and occupied the dome of the bladder. Histologically, it consisted of cyto-and syncytiotrophoblasts with extensive hemorrhage. No coexisting transitional cell ...

objective(s):green tea (gt) is one of the most popular beverages worldwide whose beneficial effects on health have been demonstrated. recent studies suggest that gt may contribute to reduction of cancer risk and progression. the aim of this study was to evaluate the effects of whole gt on urinary bladder chemical carcinogenesis in male and female icr mice. materials and methods: the gt characte...

An important variety of metaplastic lesions of the urinary bladder have been reported in the medical literature up to date. Among those of Müllerian origin, endocervicosis is the most infrequent. We report a 67 years old woman who presented with a history of left flank pain and dysuria for the past 2 months. Imaging studies revealed a solid mass in the posterior bladder wall protruding into the...

Abstract A 60-year-old male patient who has been referred by his GP to our ‘one stop hematuria clinic’ due episodes of visible for 3 months. The is Caucasian, non-smoker, drinking alcohol socially with no related family history cancer. There occupational exposure any carcinogens. Flexible cystoscopy that showed a dark coloured bladder mass arising from left side the base. CT urogram evidence so...

A 2-year-old intact female Golden Retriever presented due to rapidly progressing depression, ascites, dysuria, abdominal pain, and severe vaginal bleeding. At necropsy, the retroperitoneal space was expanded by multiple coalescing neoplastic nodules and the uterine wall was thickened with poorly defined neoplastic infiltrates. The urinary bladder was markedly thickened due to botryoid nodules e...

gross hematuria or macroscopic hematuria is a high risk urologic condition that might occur in different settings. in the case of continued gross hematuria, blood clot size may grow and lead to complete obstruction of urinary outflow. placement of three-way catheter, continuous bladder irrigation with normal saline, and cystoscopy are conventional treatments. here we introduce a case with urina...