Immunoglobulin G4-related disease (IgG4-RD) is a fibroinflammatory condition of unknown etiology, with presumed autoimmune mechanisms. It characterized by high levels IgG4 and variable clinical manifestations. can involve one or multiple organs. Herein, we reported the case 62-year-old man three organs involvement. He initially presented recurrent jaundice. Laboratory analysis revealed cholesta...

SC) is a characteristic type of SC with increased serum IgG4 levels and dense infiltration of IgG4-positive plasma cells with extensive fibrosis in the bile duct wall.1 IgG4-SC is now recognized within the spectrum of systemic IgG4-related diseases. IgG4-SC is well resolved by steroid therapy, which is a characteristic feature of IgG4-related disease. IgG4-SC is frequently associated with type ...