نتایج جستجو برای: immune efficacy
تعداد نتایج: 560214 فیلتر نتایج به سال:
The use of immune checkpoint inhibitors (iCPI) in the treatment multiple cancers has gained prominence due to their high efficacy. However, neurological immune-related adverse events (irAEs) such as myasthenia gravis (MG) have been associated with iCPI therapy. Most these irAEs are rare, and many cases, diagnoses management can be challenging. We present a case 70-year-old woman stage IIIC mela...
the toll like (family of receptors tlr) are expressed primarily by immune cells and are known to be part of innate immune system. in the past decade involvement of tlrs in several physiologic and pathologic pathways has been proved. pain transmission via glial activation is one of such interesting fields. both pathological pain states and treatment have also been shown to be related to tlr-rela...
Immune recognition of tumors can limit cancer development, but antitumor immune responses are often blocked by tumor-mediated immunosuppression. Because microbes or microbial constituents are powerful adjuvants to stimulate immune responses, we evaluated whether intratumoral administration of a highly immunogenic but attenuated parasite could induce rejection of an established poorly immunogeni...
Mastitis is a one of the major diseases of dairy animals. Staphylococcus aureus is the most common microorganism associated with this dairy scourge. Cure rates of mastitis associated with this pathogen are appallingly low. Biofilm is an important virulence factor and immunogenic structure of S. aureus that makes it resistant to phagocytosis and antibiotics. Reports on the efficacy of vaccine pr...
While the immune system protects organisms from infections, it can also react adversely to certain therapeutic interventions such as biologics that target various components of the immune system. Monitoring the responsiveness of the immune system to therapeutic interventions is crucial. This process, called immune monitoring, helps determine the safety and efficacy of therapeutic agents like va...
Adjuvant high dose IVIgs are being used increasingly in a range of immune-mediated and auto-immune diseases. Although numerous immunomodulatory mechanisms have been suggested, the exact mechanisms of action are poorly understood. The efficacy of IVIg in certain diseases has been proven in clinical trials, in so far as IVIg is approved as the therapy of choice for Kawasaki syndrome and idiopathi...
Metastatic melanoma was the first malignancy in which immune checkpoint inhibitors demonstrated their successful efficacy. Currently, the knowledge on the interaction between the immune system and malignant disease is steadily increasing and new drugs and therapeutic strategies are overlooking in the clinical scenario. To provide a comprehensive overview of immune modulating drugs currently ava...
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