treatment of severe immune thrombocytopenic purpura (itp) accompanied by life-threatening bleeding events is challenging and a combination of treatment measures should be undertaken to rapidly increase the platelet count. herein, we report a case of severe itp in a seven-year-old boy who suffered from massive bleeding which was totally unresponsive to conventional therapeutic interventions. sin...

conclusions purified lps can be considered as a safe adjuvant and can be used as a component in prophylactic and therapeutic vaccines targeting infectious disease, cancer and allergies. results biochemical analysis data and sds-page profile showed that the chemical nature of s19 lps is different from rb51 lps. both s and r-lps induce an immune response. t-cell immune response induced by both s ...

an experiment was conducted to determine the effect of different levels of potato replacing maizeseed on performance characteristicsand immunes system of broiler chicken in a completely randomized design. a total of 220 broiler chicks were randomly assigned to 5 treatment groups, with 4 replicates of 11 birds each. the chicks in the first group were fed basal diet (control), 2nd and 3rd groups ...

objective(s): iscomatrix vaccines have now been shown to induce strong antigen-specific cellular or humoral immune responses to a broad range of antigens of viral, bacterial, parasite or tumor. in the present study, we investigated the role of iscomatrix charge in induction of a th1 type of immune response and protection against leishmania major infection in balb/c mice.  materials and methods:...

background this study aimed to evaluate the effectiveness of intravenous immunoglobulin (ivig) and combination of ivig and methylprednisolone for childhood idiopathic (autoimmune) thrombocytopenia (itp) treatment; in addition investigate the related factors to develop chronic form of under 15 years itp. materials and methods this retrospective study conducted on 88 itp patients that treated wit...

in order to evaluate the effects of chlorella on broiler performance and immune system, an experimentwas performed by using 80 ross 308 male broiler chicks. the experiment was accomplished incompletely randomized design including 5 treatments with 4 replication and 4 observations in eachreplicate. the basal diet was based on corn-soybean meal (control) and without any additives. agraded level o...

background: occupational exposure to cotton dust, fibers, metal fumes and different chemicals used in the apparel manufacturing industries cause a wide range of physical and psychological health problems in the garment workers that may also affect their immune function. objective: to assess the immune system function in garment workers. methods: a total of 45 workers of a garment factory, and 4...

abstract background immune thrombocytopenic purpura (itp) is the most prevalent cause of thrombocytopenia in children. despite the importance of itp in children under 2- years old, only a few publications are available in the literature. itp usually presents itself as   isolated thrombocytopenia and mucocutaneous bleeding. materials and methods this study was conducted on 187 under 2- year-old ...

Sunitinib is an oral tyrosine kinase inhibitor which prevents tumor growth and metastatic progression. It was approved for treatment of advanced renal cell cancer, gastrointestinal stromal tumor and advanced pancreatic neuroendocrine tumors. It has several adverse reactions on multi organ systems including hematologic system. Although the neutropenia and thrombocytopenia commonly happens as Gra...