Eosinophilic colitis is an idiopathic inflammation of the alimentary canal and is characterized by infiltration of the intestinal wall by eosinophils, massive submucosal edema, and peripheral eosinophilia. However, the presence of eosinophils in a colon biopsy requires thorough searching for secondary causes and eosinophilic colitis remains a diagnosis of exclusion. A 67-year-old male patient u...

OBJECTIVE to describe the experience at two tertiary centres during the first year of use of magnetic resonance enterography (MRE) for the management of Crohn's disease (CD): indications and influence of the technique in clinical decision making. MATERIALS AND METHODS retrospective descriptive study in which patients who underwent MRE were included consecutively. Epidemiological and clinical ...

When treating Crohn disease (CD) with thiopurines, achievement of an objective response is essential. However, the minimal degree of mucosal improvement required to alter disease outcomes of CD is unknown.To determine the endoscopic responses of thiopurine monotherapy and to determine the minimal degree of mucosal improvement required to alter disease outcomes of CD.One hundred thirty CD patien...

Crohn’s disease (CD) is a chronic inflammation of the intestines that follows a relapsing or remitting course. Endoscopic imaging and radiological imaging are essential for diagnosis and to assess disease severity, response to treatment, and complications. CD most commonly affects the terminal ileum, which is accessible with conventional ileocolonoscopy. Nevertheless, jejunal lesions are presen...

BACKGROUND We investigated a consecutive series of children with chronic enterocolitis and regressive developmental disorder. METHODS 12 children (mean age 6 years [range 3-10], 11 boys) were referred to a paediatric gastroenterology unit with a history of normal development followed by loss of acquired skills, including language, together with diarrhoea and abdominal pain. Children underwent...

INTRODUCTION Due to limitation of colonoscopy in assessing the entire bowel and patients' intolerance in inflammatory bowel disease (IBD), in the current study, we aimed to prospectively compare the accuracy of 99mTc(V)-dimercaptosuccinic acid (DMSA) and fecal calprotectin with ileocolonoscopy as new methods for localizing inflammations. METHODS Current prospective study conducted between 2012 ...

http://dx.doi.org/10.1016/j.jpge.2015.10.006 2341-4545/© 2015 Sociedade Portuguesa de Gastrenterologia. Published CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4 emorrhagic shock, requiring substantial transfusion suport (10 units of erythrocyte concentrate, 4 units of resh frozen plasma, 1 platelet pool and 3 g of fibrinoen), renal and respiratory failure with the need of n...

Purpose To evaluate and compare the mesenteric and bowel wall changes during Crohn's disease (CD) on ultrasonography (US) Strain Elastography (SE) and Enterography Magnetic Resonance Imaging (E-MRI). Methods From July 2014 to September 2016, 35 patients with ileocolonoscopy diagnosis of CD were prospectively examined with E-MRI and in the same time with US and SE. Results A total of 41 affe...

Background: The association between spondyloarthropathy and Crohn’s disease is well known. A risk for evolution to Crohn’s disease has already been shown in the subgroup of patients with spondyloarthropathy associated with chronic gut inflammation. Objective: To investigate whether the reported polymorphisms in the CARD15 gene, a susceptibility gene for Crohn’s disease, are associated with the ...