نتایج جستجو برای: il2ra
تعداد نتایج: 257 فیلتر نتایج به سال:
Diabetes adalah suatu keadaan adanya gangguan metabolik yang terjadi jangka panjang/kronis ditandai dengan tingginya kadar glukosa darah disebabkan oleh defisiensi insulin absolut maupun relatif, disfungsi sel β, resistensi atau dapat keduanya. melitus secara diklasifikasikan menjadi beberapa jenis, dan paling umum diketahui diabetes tipe 1 2. Faktor-faktor berhubungan angka kejadian DM diantar...
UNLABELLED Genetic lesions such as BCR-ABL1, E2A-PBX1, and MLL rearrangements (MLLr) are associated with unfavorable outcomes in adult B-cell precursor acute lymphoblastic leukemia (B-ALL). Leukemia oncoproteins may directly or indirectly disrupt cytosine methylation patterning to mediate the malignant phenotype. We postulated that DNA methylation signatures in these aggressive B-ALLs would poi...
Background/objective — The goal of our study was to investigate the role interaction between polymorphic loci immune response mediator genes (TNFA rs1800629, LTA rs909253, IL1B rs16944, IL2-IL21 rs6822844, IL2RA rs2104286, IL6 rs1800795, IL10 rs1800872, MIF rs755622, CTLA4 rs3087243, NFKB1 rs28362491, PTPN22 rs2476601, and PADI4 rs2240336) in formation a genetic predisposition juvenile idiopath...
Association of IL2RA and IL2RB with rheumatoid arthritis: a replication study in a Dutch population.
OBJECTIVES Rheumatoid arthritis (RA) shares some similar clinical and pathological features with juvenile idiopathic arthritis (JIA); indeed, the strategy of investigating whether RA susceptibility loci also confer susceptibility to JIA has already proved highly successful in identifying novel JIA loci. A plethora of newly validated RA loci has been reported in the past year. Therefore, the aim...
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