to define efficacy of pre-operative chemotherapy in down staging of advanced non-round cell soft tissue sarcomas. from sep 2002 to dec 2005, 70 patients were treated by ifosfamid, mesna, cisplatin, adriamycin, mitomycin and subsequent surgery. postoperatively, patients received radiotherapy in cases of microscopically incomplete resection or local recurrence. the median age of the patients was ...

results the results showed that the mean scores of nausea in the control group was increased from 2.97 on the first day to 3.26 and in the intervention group was decreased from 3.44 to 1.52 at the end of trial. however there was not any significant difference in the first, second, third and fourth days between two groups. conclusions massage can reduce nausea. however further studies with large...

background stomatitis is a disturbing side-effect of chemotherapy that disturbs patients and causes difficulties in patient’s drinking, eating and talking, and may results in infection and bleeding. objectives this study aimed to investigate the effect of yarrow distillate in the treatment of chemotherapy-induced stomatitis. patients and methods rapy-induced oral stomatitis referred to shahid b...

background deep vein thrombosis (dvt) is a well-recognized complication in patients with cancer. chemotherapy and cancer surgery increase the risk of dvt in these patients. there are a few reports about the prevalence of dvt in patients with cancer regarding different managing modalities. objectives this study aimed to assess the prevalence of dvt in patients with cancer, who were hospitalized ...

background: ketamine increases blood pressure and heart rate. propofol is an anesthetic drug with rapid recovery, but it causes respiratory depression, low heart rate and low blood pressure. combination of ketamine and propofol provides sedation, analgesia, and rapid recovery with hemodynamic stability and minimal respiratory depression. there have been a few studies about the effect of differe...

background: mucositis is a complex inflammatory response of the digestive system mucous membrane and it is also one of the most common painful side effects following chemotherapy in children with carcinoma. developing to mucositis affects the patient's life severely and can lead to long – term hospitalization.therefore, this study was conducted to evaluate the effect of chamomile mouthwash on t...

background: today the use of laparoscopy before laparotomy is an effective method for decision-making in patients with gastric adenocarcinoma. the reliance on ct scans for decision-making purposes is not only unhelpful, yet also misleading . nonetheless, indications for laparoscopy and its application are changing daily. the low quality of diagnostic tools and epidemiological situation in our c...

abstract background: nausea and vomiting are the worst and the most prevalent complications experienced by 70–80% of patients. complementary treatments including therapeutic touch are cost‑effective and low‑risk, independent nursing interventions. present research aims at investigating the effect of therapeutic touch on the intensity of acute chemotherapy‑induced vomiting in these patients. mat...

abstract background: fatigue is the most common side effect of chemotherapy in children with acute lymphoblastic leukemia (all).acupressure is one of the most popular non‑pharmacologic methods used to reduce fatigue in other settings. the aim of the study was to evaluate the effect of acupressure on reducing fatigue among children with all compared with a placebo treatment. materials and method...

paclitaxel is a highly effective anticancer agent. it is active against a broad range of cancers that are generally considered refractory to conventional chemotherapy. paclitaxel induces a peripheral neuropathy (pn) that is characterized by sensory symptoms such as numbness and paresthesia in a glove and stocking distribution. pn may be severe and dose limiting at initial doses above 275 mg/m2....