BACKGROUND Risk factors and outcomes in hematological patients who acquire invasive fungal sinusitis (IFS) are infrequently reported in the modern medical era. METHOD A retrospective study of hospitalized patients with hematological disease was conducted at National Taiwan University Hospital between January 1995 and December 2009. RESULTS Clinical characteristics and outcomes with their as...

OBJECTIVE To investigate the possible protective effect of recombinant human interleukin-11 (rhIL-11) against ifosfamide (IFS)-induced hemorrhagic cystitis (HC). MATERIALS AND METHODS Male Swiss mice (20-30g) were pretreated with rhIL-11 (25-625 mg, subcutaneously.) 30 min before intraperitoneal injection of IFS (400 mg/kg) or with saline (control group). Twelve hours later, HC was evaluated ...

Keratins K1 and K10 are the most abundant proteins in the upper epidermis where they polymerize to form intermediate filaments (IFs). In addition to their well-established function in providing epidermal stability, K1/K10 (i.e. the dimer between K1 and K10) IFs are supposed to be important for terminal epidermal differentiation and barrier formation. It was previously shown that the imbalanced ...

Introduction: Invasive fungal rhinosinusitis is a challenging condition that can be found mostly in immunocompromised patients. Failure to diagnose and treat this entity promptly usually results in rapid progression and death. The purpose of this study was to determine clinical presentation, complication and morbidity in patients with acute versus chronic invasive fungal rhinosinusitis. Setting...

We consider the distribution of the intermediate filaments (IFs) in the retinal cells of the Pied flycatcher (Ficedula hypoleuca, Passeriformes, Aves) in the foveolar zone, which has the most specialized morphology, where the passerines have neither the rods nor the second-order neurons that service these rods, with only the single and double cones acting as photoreceptors. We report that singl...

I applaud the ASM for the decision to put their head above the parapet and cast aside the essentially meaningless metric of journal impact factor (IF). What began as a measure intended to allow quantitative evaluation of the importance of journals, IFs have virtually consumed all other (often more relevant) considerations regarding quality of publication. Ironically, for many of the scientists ...

The research for this report was produced under the auspices of the IFS Savings Consortium, to whom the authors are grateful for financial assistance and many useful discussions and comments in the series of seminars over the last four years. The members of the IFS Savings Consortium are: Acknowledgements The research in this report was funded by the IFS Savings Consortium and co-funded by the ...

Intermediate filaments are a large and structurally diverse group of cellular filaments that are classified into five different groups. They are referred to as intermediate filaments (IFs) because they are intermediate in diameter between the two other cytoskeletal filament systems that is filamentous actin and microtubules. The basic building block of IFs is a predominantly alpha-helical rod w...

OBJECTIVE The aim of the present study was to determine the prevalence and reporting rate of incidental findings (IF) in adult outpatients undergoing lumbar magnetic resonance imaging (MRI). MATERIALS AND METHODS Re-evaluation of a total of 1278 lumbar MRI images (collected from patients with a mean age of 50.5 years, range 16-91 years) captured between August 2010-August 2011 was done by a n...