The human cytomegalovirus (HCMV) tegument protein pp71, encoded by gene UL82, stimulates viral immediate-early (IE) transcription. pp71 interacts with the cellular protein hDaxx at nuclear domain 10 (ND10) sites, resulting in the reversal of hDaxx-mediated repression of viral transcription. We demonstrate that pp71 displaces an hDaxx-binding protein, ATRX, from ND10 prior to any detectable effe...

The UL3 protein of equine herpesvirus 1 (EHV-1) KyA strain is a homolog of the ICP27 alpha regulatory protein of herpes simplex virus type 1 (HSV-1) and the ORF 4 protein of varicella-zoster virus. To characterize the regulatory function of the UL3 gene product, a UL3 gene expression vector (pSVUL3) and a vector expressing a truncated version of the UL3 gene (pSVUL3P) were generated. These effe...

H ier w o rd ’n o o r s ig g e g e e v a n d ie loop b an e v a n d ie 139 g ereg istreerd e v erp leeg k u n d ig es w a t’n B .S o c .S c . (V erp leeg k u n d e) graad aan d ie U n iv e r s ite it v a n N a ta l b eh a a l het. V an die p o te n s ië le 981 w erk ja re w a t h ierd ie gegra d u eerd es so u k o n g ew erk h et, is 551 jaar (56,2%) m et v e r p le e g w e r k d eu rg eb rin g...

UNLABELLED It was our purpose to evaluate the clinical impact of systematic PET/CT for the diagnosis of infectious embolisms in patients with infectious endocarditis (IE) in comparison with a historic cohort of IE patients managed without this technique. Detection of extracardiac lesions is an essential component of the management and outcome of IE. Studies using PET/CT for the evaluation of pa...

Alkaloids are aromatic hydrocarbons with nitrogen as heteroelements in the ring structure that responsible for bonding metal surface and help to reduce corrosion of metals such mild steel (MS) an acidic medium. In this study, alkaloid Rhynchostylis retusa (RR) was extracted by solvent extraction method confirmed chemical test well FTIR spectroscopic test. Extracted alkaloids were tested green i...

Infective endocarditis (IE) is a potentially fatal disease that primarily caused by Staphylococci and Streptococci. The HACEK group of bacteria (Hemophilus species, Aggregatibacter Cardiobacterium hominis, Eikenella corrodens, Kingella kingae) account for only 1-3% reported IE cases. has long been known to cause glomerulonephritis. most common histologic patterns seen are crescentic diffuse pro...

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