We present the following results about IDA* and related algorithms: We show that IDA* is not asymptotically optimal in all of the cases where it was thought to be so. In particular, there are trees satisfying all of the conditions previously thought to guarantee asymptotic optimality for IDA*, such that IDA* will expand more than O(N) nodes, where N is the number of nodes eligible for expansion...

Abscission is a developmental process that enables plants to shed unwanted organs. In Arabidopsis, the floral organ abscission is regulated by a signaling pathway consisting of the peptide ligand IDA, the receptor-like kinases (RLKs) HAE and HSL2, and a downstream MAP kinase (MAPK) cascade. However, little is known about the molecular link between ligand-receptor pairs and intracellular signali...

A practical method for accurate evaluation of the Coulombic contribution to the electronic coupling for energy transfer at any donor-acceptor separation is reported. The method involves the exact interaction between transition densities of each chromophore which are calculated ab initio and may include electron correlation. The method is used to calculate coupling strengths between the pigments...

Inflammation can lead to malabsorption of important micronutrients such as iron. Malabsorption and nutritional deficiency can be caused by a variety of pathological and environmental factors causing a range of other symptoms commonly caused by both H. pylori infection and coeliac disease (CD). National guidelines suggest the routine taking of duodenal biopsies to exclude CD when investigating p...

Pre-donation screening declarations and hemoglobin (Hb) testing are measures used to determine the quality of donated blood. The copper sulphate (CuSo4) method used to screen for blood abnormalities can give inaccurate results if strict quality control is not applied. Blood donors who are carriers of thalassemia and those with mild iron deficiency anemia (IDA) are usually asymptomatic and frequ...

Cristina Maria Areias, Benedita Sampaio-Maia, Hercilia Guimaraes, Paulo Melo, David Andrade I Odontopediatrics, Faculdade de Medicina Dentária da Universidade do Porto, Porto, PT. II Microbiology, Faculdade de Medicina Dentária da Universidade do Porto, Porto, PT. III Pediatrics, Faculdade de Medicina Universidade do Porto, Porto, PT. IV Dentistry, Faculdade de Medicina Dentária da Universidade...

Plants constantly renew during their life cycle and thus require to shed senescent and damaged organs. Floral abscission is controlled by the leucine-rich repeat receptor kinase (LRR-RK) HAESA and the peptide hormone IDA. It is unknown how expression of IDA in the abscission zone leads to HAESA activation. Here we show that IDA is sensed directly by the HAESA ectodomain. Crystal structures of H...

Background: Iron deficiency, is a common worldwide complication, especially in preschool children. Iron deficiency anemia (IDA) is associated with changes in the mental and motor development, defects of immune system, cardiovascular, diseases and disruption of lipid profile. In IDA, the occurrence of dyslipidemia is controversial. We aimed to investigate the association between IDA and serum li...

Two recent methods, Neighborhood Components Analysis (NCA) and Informative Discriminant Analysis (IDA), search for a class-discriminative subspace or discriminative components of data, equivalent to learning of distance metrics invariant to changes perpendicular to the subspace. Constraining metrics to a subspace is useful for regularizing the metrics, and for dimensionality reduction. We intro...

We present ab initio transition density cube (TDC) calculations of the coulombic couplings between chlorophyll and carotenoid pigments in the major light-harvesting complex of photosystem II (LHC II) based on the 2.72 Å structure [Liu et al., Nature 428(2004) 287– 292]. A comparison with couplings calculated by the ideal dipole approximation (IDA) demonstrate that for inter-pigment distances of...