The aim of the present paper is to define and study (IC)$LM$-fuzzytopological spaces, a generalization of (weakly) induced $LM$-fuzzytopological spaces. We discuss the basic properties of(IC)$LM$-fuzzy topological spaces, and introduce the notions ofinterior (IC)-fication and exterior (IC)-fication of $LM$-fuzzytopologies and prove that {bf ICLM-FTop} (the category of(IC)$LM$-fuzzy topological ...

We studied the effects of tick saliva on cell migration, cell signaling, phagocytosis, and gene expression in the murine macrophage cell line, IC-21. Saliva increased both basal- and platelet-derived growth factor (PDGF)-stimulated migration in IC-21 cells. However, saliva did not affect PDGF-stimulated extracellular signal-regulated kinase (ERK) activity. Zymosan-mediated interleukin-1 recepto...

Human noroviruses are the dominant cause of outbreaks of acute gastroenteritis. These viruses are usually detected by molecular methods, including reverse transcriptase PCR (RT-PCR) and enzyme-linked immunosorbent assay (ELISA). Human noroviruses are genetically and antigenically diverse, with two main genogroups that are further subdivided into over 40 different genotypes. During the past deca...

Introduction: Laboratory diagnosis of Corona Virus Disease- 2019 (COVID-19) plays a major role in diagnosing and treating infection. The corner stone strategic public health interventions breaking the chain transmission was diagnostic laboratory testing case-based data. purpose study to establish quality control standards for RT-PCR by performing Root Cause Analysis (RCA) invalid Internal Contr...

We study Vand Λ-patterns which generalize valleys and peaks, as well as increasing and decreasing runs, in permutations. A complete classification of permutations (multi)-avoiding Vand Λ-patterns of length 4 is given. We also establish a connection between restricted permutations and matchings in the coronas of complete graphs.

AIMS To investigate the role of urinary BK polyoma virus (BKPyV) in the pathophysiology and prognosis of patients with painful bladder syndrome/interstitial cystitis (PBS/IC). METHODS Urine samples were collected from 15 patients with PBS/IC and 8 control patients (with urolithiasis, overactive bladder and benign prostatic hyperplasia). BKPyV titres were quantitatively determined using real t...

PURPOSE To evaluate the expression patterns of cytokeratin (K) 12, 13, and 19 in normal epithelium of the human ocular surface to determine whether K13 could be used as a marker for conjunctival epithelium. METHODS Total RNA was isolated from the human conjunctiva and central cornea. Those transcripts that had threefolds or higher expression levels in the conjunctiva than the cornea were iden...

Chronic pain may accompany immune-related disorders with an elevated level of serum IgG immune complex (IgG-IC), but the underlying mechanisms are obscure. We previously demonstrated that IgG-IC directly excited a subpopulation of dorsal root ganglion (DRG) neurons through the neuronal Fc-gamma receptor I (FcγRI). This might be a mechanism linking IgG-IC to pain and hyperalgesia. The purpose of...

Myosin IC is a single headed member of the myosin superfamily. We recently identified a novel isoform and showed that the MYOIC gene in mammalian cells encodes three isoforms (isoforms A, B, and C). Furthermore, we demonstrated that myosin IC isoform A but not isoform B exhibits a tissue specific expression pattern. In this study, we extended our analysis of myosin IC isoform expression pattern...