alzheimer's disease (ad) is a progressive neurodegenerative disease characterized by memory and cognitive dysfunction due to neuronal cell loss in higher brain centers. senile plaques containing amyloid β (aβ) are associated with this disease as well as a reduction in cholinergic neuron numbers. tacrine is a reversible cholinesterase inhibitor in clinical use to treat moderate forms of ad. chit...

interleukin-12 (il-12) is a key cytokine involved in regulating the balance between th1 and th2 cells by promoting th1 response. a reduced capacity to produce this cytokine could lead to aberrant th2 development. on the same aspect significant impact of il-12 on invariant natural killer t (inkt) cells was reported. therefore, we examined the serum levels of il-12 and the absolute number of peri...

a synoptic method based on stream analysis is applied to understand the governing mechanism of summer rainfall occurrence in the south of iran. based on this, the rainfall data of 152 stations of iran were analyzed for a 33-year period (1970-2002). investigating the spatial and temporal distribution of summer rainfall, a typical rainy region is recognized in the south east of iran. it is found ...

main objective in wheat breeding programs is to improve high yielding and stable varieties possessing desirable morpho-physiological traits. this study was conducted to determine the stability of 18 winter and facultative bread wheat genotypes. the experiments carried out in 9 experimental stations (karadj- arak- ardebil- jolgerokh- miandoab- hamedan- mashad- qazvin- khoy) using a randomized co...

utilization of the new compatibilizers to improve matrix/filler interface adhesion and also, nanoparticles to improve the properties of wpc products have always been of interest to researchers. in this study, the effect of oxidized polypropylene in solution phase as a comptibilizer and nanoclay particles on the physical and mechanical properties of wood fiber reinforced polypropylene composite ...

the genus eremostachys (lamiaceae), consists of about 60 species which 15 species of eremostachys grow wildly in the north-west of iran. the rhizomes and roots of e. laciniata have traditionally been used as a local analgesic and for the treatment of rheumatic diseases and pain in the feet. this experiment was conducted in the north-west of iran in 2012-2013, to evaluate morphological diversity...

trehalose is an important disaccharide signal metabolite in plants which is involved in various aspects of plant function such as response to stress, photosynthesis and carbon allocation and partitioning. a mutant of arabidopsis lacking trehalose-6-phosphate synthase activity (tps1) accumulates ascorbate. exogenous ascorbate application ameliorates trehalose induced growth inhibition of wild ty...

background: selective phosphodiesterase (pde3) inhibitors improve cardiac contractility and may use in congestive heart failure. however, their proarrhythmic potential is the most important side effect. methods: in this research, we evaluated the potential cardiotonic activity of six new synthesized selective pde3 inhibitors (6-hydroxy-4-methylquinolin-2(1h)-one derivatives) using the spontaneo...

in this report, synthesis, characterization and application of silica perchloric acid nanosphere as a novel and heterogeneous catalyst is described. these nanospheres have been characterized by xrd, ft-ir, bet and tga spectra and also by sem and tem images. the results show that it has a spherical shape and the particles size are between 75 and 100 nm. the catalytic activity has been investigat...

shortage of irrigation water, being a crucial problem in arid and semiarid regions, makes it necessary to use treated wastewater in agriculture. a field experiment was conducted to investigate the effect of treated municipal wastewater (tmw) on the yield and fiber quality of cotton (gossypium hirsutum l.) (mehr variety). treated municipal wastewater was supplied from shahrake ghods sewage treat...