As a first step towards improving the aqueous stability of 9-aminocamptothecin (9AC), a detailed kinetic and thermodynamic investigation of the hydrolysis reaction of 9AC was carried out, using a first derivative absorption spectrophotometry technique. It was found that 9AC-lactone decayed with a half-life of 25 min in PBS at pH 7.4 and 310.15K. The activation energy (Ea) associated with the hy...

A rational-expectations equilibrium with positive demand for financial information does exist under fully revealing asset price—contrary to a wide-held conjecture. Whereas a continuum of investors is inconsistent with fully revealing equilibrium, finitely many investors with average portfolios demand information in equilibrium if they can adjust portfolio size in an additive-signal return model...

Using the fixed point method, we prove the generalized Hyers-Ulam-Rassias stability of the following functional equation in multi-Banach spaces:begin{equation} sum_{ j = 1}^{n}fBig(-2 x_{j} + sum_{ i = 1, ineq j}^{n} x_{i}Big) =(n-6) fBig(sum_{ i = 1}^{n} x_{i}Big) + 9 sum_{ i = 1}^{n}f(x_{i}).end{equation}

Hydrogen and helium transmission signals trace the upper atmospheres of hot gas-giant exoplanets, where incoming stellar extreme ultraviolet X-ray fluxes are deposited. Further, for hottest stars, near-ultraviolet excitation hydrogen in Balmer continuum may play a dominant role controlling atmospheric temperature driving photoevaporation. KELT-9 b is archetypal example such an environment as it...