in this paper, the antigen and gene frequencies of class i hla antigens were evaluated in 1000 individuals in khorasan province in northeast iran, and compared with statistics of other countries. the results and a general discussion are presented.

molecular genetics selection on individual genes is a promising method to genetically improve economically important traits in livestock. the insulin like growth factor-i (igf-i) gene may play important roles in growth of multiple tissues, including muscle cells, cartilage and bone. the objectives of the present study were the estimate the haplotype frequencies of the igf-i gene polymorphisms i...

angiotensin converting enzyme (ace; omim: 106180) has an important role in the conversion of angiotensin i to angiotensin ii and degradation of bradykinin. genetic polymorphism i/d (rs4646994) in the gene encoding ace has been well defined. to get more insight into the genetic structure of iranian populations, the distribution of the ace i/d polymorphism among iranians was compared with each ot...

background and aims: virus infections represent some of the most important diseases of lily, plants because of the devastating effects caused to the crops and the absence of effective treatments. a survey for virus diseases of lilies, revealed the occurrence of cucumber mosaic virus (cmv) in plants growing in tehran province, iran. materials and methods: during 2013, 50 lily samples with virus-...

the aim of the study was to explore the mechanisms underlying the association of birth weight with later body mass index (bmi) from the biochemical markers related to metabolism and the apa i polymorphism in igf-ii gene.a total of 300 children were selected randomly from the macrosomia birth cohort in wuxi, china. the height and weight were measured and blood samples were collected. plasma conc...

background: antibiotic resistance and the need for long-term treatments especially for chronic infections necessitate the developmentof a vaccine against pseudomonas aeruginosa infection.objectives: in this study, recombinant exotoxin a (domains i and ii), (exoa i-ii) protein was expressed, purifid and its immunologicalcharacteristics were evaluated in a mouse model.materials and methods: the g...

Background: Killer cell immunoglobulin-like receptors (KIR) are expressed on NK cells and a subset of T cells. The variable KIR receptors along with their ligands, HLA class I, influence risk for autoimmune and malignant diseases. Objective: To investigate the KIR gene profiles in relation to susceptibility to Graves’ disease in patients with ophthalmopathy. Methods: KIR genes profiles were ana...