Rapid induction of soldiers to high altitude under emergency situation may lead higher incidence acute mountain sickness (AMS) and other illness. Intermittent Hypoxia Training (IHT) at sea level before going is an approach for rapid acclimatisation. This be helpful reduce the occurrence AMS leads better acclimatisation in shorter duration. The present study evaluates role biochemical markers af...

The present work studied the effect of calcium channel blocker (nimodipine) on epileptic seizures elicited by electrical stimulation of somatosensory cortex in young rats exposed to hypoxia. Rats were exposed to different patterns of short-term hypoxia (hypobaric or normobaric) and reactions of cortical neurones were registered. In the youngest animals (12-day-old), the effect was minimal, in o...

Because it has been reported that hypoxia in rats may promote lipid peroxidation and other free radical reactions that could modify membrane lipids and proteins, the effect of acute hypobaric hypoxia on human erythrocyte membranes was investigated. 12-(1-Pyrene)dodecanoic acid fluorescent probe was used to assess short-range lateral diffusion status in the membrane bilayer. Membrane protein mod...

In this study, changes in heart rate variability (HRV) induced by exposure to hypoxia were evaluate in healthy male. The sample entropy as a non-linear method of HRV analysis was used; it’s a powerful way to analyze biological system. Our aim was to investigate the influence of stepwise hypoxia on HRV using sample entropy, we tested nine healthy yellow males (age=35 ± 5) at 3600m, 4000m, 4400m,...

We hypothesized that activation of angiogenesis by chronic hypoxia may affect vascular resistance and, subsequently, blood pressure levels in spontaneously hypertensive rats (SHRs). Five-week-old prehypertensive SHRs and age-matched normotensive Wistar-Kyoto (WKY) rats (n=8 per group) were maintained under normobaric normoxic or hypoxic (10% O(2)) conditions for 8 weeks. Three weeks later, the ...