many formulae and figures. Its many chapter subheadings give the book its rather terse, outline form. A discussion of methods of isolation, characterization, and determination of purity is followed by successive chapters dealing with reaction rates as a function of substrate concentration, inhibitor action, temperature, and pH. Thermodynamic concepts are well developed in chapters on energetics...

in studies on teratogenesis. Fetuses afflicted with holoprosencephaly, including varying degrees of such malformations as pituitary agenesis, cyclocephaly, cyclopia and monorhinia, can be obtained by administering triparanol or AY 9944 which inhibits cholesterol synthesis. A large number of fetuses have a minor form of holoprosencephaly, i.e. limited to isolated hypophyseal agenesis. We used th...

OBJECT Spontaneous meningoencephaloceles of the lateral sphenoid sinus are rare lesions that are hypothesized to result from persistence of the lateral craniopharyngeal canal. Prior reports of the management of this lesion have been limited by its relative rarity. The objective of this paper is to report the theoretical etiology, surgical technique, and outcomes in patients undergoing endoscopi...

Neuroendocrine dysfunction is a common complication of several neurosurgical conditions. In particular, central diabetes insipidus (CDI) can occur subsequent to traumatic brain injury, subarachnoid hemorrhage, cerebral tumors or as result following pituitary neurosurgery. contrast, surgical resection non-sellar does not commonly in CDI, with only few cases reported the literature. We report cas...

hypothalamic-hypophyseal complex, the gonads, pancreatic islet cells, adrenal glands, thyroid glands, parathyroid glands, ultimobranchial glands and the endocrine cells of the gut. All these organs release hormones into the bloodstream, which act on target tissues by interacting with receptors on the surface of the cell (peptide hormones) or within the cytoplasm or nucleus of the cell (steroid ...