In this study, we investigated the prognostic value of serum sodium and hyponatremia (< or =130 mEq/L) in 262 cirrhotic patients consecutively listed, 19 of which died (7%), 175 survived (67%), and 68 underwent liver transplantation (26%) during 3 months of follow-up. Hyponatremia was present in 63% of patients who died, compared to 13% of those who survived (P < .001), whereas the proportion w...

A 72-year-old man was hospitalized with asymptomatic hyponatremia. Despite hyponatremia, urinary sodium excretion with urine osmolality exceeding plasma osmolality persisted. Plasma vasopressin levels were high and independent of plasma osmolality during hypertonic saline infusion. Computed tomography of the chest showed enlarged mediastinal and right hilar lymph nodes. Microscopically, a speci...

Hyponatremia is the most common electrolyte disorder that requires careful management. Water intoxication with hyponatremia is rare condition that originated from overhydration. Water intoxication, also known as dilutional hyponatremia, develops only because the intake of water exceeds the kidney's ability to eliminate water. Causes of this water intoxication include psychiatric disorder, force...

The authors regret that there was a spelling mistake in points two and three of their highlights. This has now been corrected, as shown below: A high frequency of hyponatremia following ESL therapy was found (4/32). ESL related hyponatremia occurs in elderly stroke patients with comorbidities. ESL related hyponatremia is not dose related. Sodium levels need to be monitored in elderly on ESL the...

Guillain-Barré (GBS) syndrome is an immune-mediated polyneuropathy that frequently presents with progressive muscle weakness. Hyponatremia is rarely the presenting feature of this demyelinating process, as it is normally described following the diagnosis. We report a case of Guillain-Barré syndrome diagnosed after presenting symptoms of severe hyponatremia. Awareness should be raised for consid...

Adrenocortical insufficiency such as occurs in Addison's disease causes hyponatremia and renal tubular acidosis (RTA). Hyponatremia results from both aldosterone and cortisol insufficiency. RTA is due to aldosterone insufficiency. The involvement of cortisol in RTA is unclear. Here, we report a woman in her 70s who was admitted to our hospital with severe hyponatremia (106 mEq/l) and RTA. The p...

The syndrome of inappropriate antidiuretic hormone secretion (SIADH) results from the aberrant or sustained secretion of the antidiuretic hormone. Classic manifestations include water retention, hyponatremia, and hypo-osmolality of the serum. Treatment is aimed at differentiating SIADH from other causes of hyponatremia, determining the underlying disorder, and alleviating the excessive water re...

Hyponatremia is a common complication after subarachnoid hemorrhage. Although the mechanism of hyponatremia is still controversial, cerebral salt wasting syndrome is currently more favored over the the syndrome of inappropriate secretion of antidiuretic hormone. To accurately manage body water and electrolytes in the acute stage of subarachnoid hemorrhage, we prospectively studied the relations...

Decreases in the concentration of sodium in plasma constitute hyponatremia, the commonest electrolyte disorder in clinical medicine. It is now well established that its presence conveys an increased mortality risk even when the decrement is mild. In addition, recent evidence suggests that chronic and apparently asymptomatic hyponatremia is associated with increased morbidity including neurocogn...

abstract a 71-year-old male with a long history of diabetes and hypertension was admitted with mild azotemia and recurrent hyponatremia. he was diagnosed with a pituitary gland cystic tumor. on careful evaluation, his hyponatremia was found to be due to cerebral salt wasting. the patient made a full recovery following treatment for cerebral salt wasting.