PURPOSE The translabyrinthine approach to acoustic neuroma resection offers excellent exposure for facial nerve dissection with 95% preservation of anatomic continuity. Acceptable outcome in facial asymptomatic patients is reported at 64-90%, but transient postoperative deterioration often occurs. The objective of this study was to identify preoperative clinical presentation and intraoperative ...

INTRODUCTION Cholesteatoma is a destructive lesion that can result in life-threatening complications. Typically, it presents with hypoacusis and continuous otorrhea as symptoms. Because it is a rare disease, there are few studies in Brazil describing the characteristics of patients with the disease. OBJECTIVE This study aimed to determine the prevalence of cholesteatoma in patients with chron...

TO THE EDITOR—We read with interest the article by Collins and colleagues demonstrating that nontypeable Haemophilus influenzae (NTHi) is responsible for most invasive disease occurring in the perinatal period and that early-onset neonatal NTHi disease (strain isolation from blood or cerebrospinal fluid within 48 hours of birth) is strongly associated with premature birth [1]. Although it is we...

INTRODUCTION AND OBJECTIVES Sensory neural hearing loss (SNHL) is a disorder characterised by an important deterioration of the auditory function. Re-establishing normal ion homeostasis of the endolymph could be related to hearing recovery and it might be mediated by mineralocorticoids. The main purpose of this preliminary, randomized controlled clinical trial was assessing the recovery of idio...

Necrotizing otitis externa is a potentially lethal infection that starts in the external auditory canal and may progress to the skull base. It happens in elderly diabetic patients and is associated to a high morbi-mortality rate. The major causal agent is Pseudomonas aeruginosa, in 96 to 98% of the cases. The infection extends from the osteocartilaginous junction to the temporal bone by means o...

BACKGROUND Recent clinical and animal experimental studies postulate that the pathogenetic mechanisms of vitiligo could be of systemic origin as vitiligo is associated with ocular and auditory abnormalities as well as other autoimmune disorders.Hence, we studied genetic factors, systemic associations, ocular and auditory abnormalities of vitiligo. METHODS The study group included 150 new case...

Abstract Background CHARGE syndrome (CS) is a rare genetic disease characterized by constellation of clinical findings including Coloboma, Heart defects, choanal Atresia, Retardation growth and/or development, Genitourinary malformation and Ear abnormalities. We present case persistent fifth aortic arch (PFAA), an extremely congenital anomaly (AA), in child with genetically confirmed CS perform...

INTRODUCTION Growth hormone deficiency (GHD) is one of the main indications for growth hormone therapy. One characteristic of this disease is bone age delay in relation to the chronological age. Pituitary dysfunction negatively affects the growth and development of the jaws and teeth of the child. The secretion of endocrine glands regulates growth, development, and gender differentiation. It al...

Onset of MELAS due to the m.3243ANG mutation is early if the large phenotypic variability is considered ☆ , ☆☆ Keywords: mtDNA m.3243ANG MELAS Gene Mitochondrial disorder Stroke-like episode Letter to the Editor With interest we read the article by Sunde et al. about a female with MELAS syndrome with onset at age 49 years and four stroke-like episodes (SLEs) during the first 2 years who was fol...

Internal auditory meatus stenosis is defined as a loss of 3mm or more in the vertical diameter of the internal acoustic meatus, or even as a meatus smaller than 2mm. Inner ear abnormalities may occur in about 20% of the cases of patients who have sensorineural hearing loss (Figure 1). This loss may happen because of alterations in the VIII cranial nerve (vestibulococlear). In most cases, it hap...