نتایج جستجو برای: hypo

تعداد نتایج: 4859  

2017
Alexandre A da Silva John E Hall Jussara M do Carmo

The hypothalamic-pituitary-adrenal (HPA) axis has been postulated to play a major role in mediating the antidiabetic effects of leptin. We tested if the pituitary is essential for the chronic central nervous system mediated actions of leptin on metabolic and cardiovascular function in insulin-dependent diabetic and non-diabetic rats. Male 12-week-old hypophysectomized Sprague-Dawley rats (Hypo,...

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2005
Marcia R Batista Marta S Smith Wanda L Snead Cynthia C Connolly D Brooks Lacy Mary Courtney Moore

We evaluated the effect of chronic (3 wk) subcutaneous treatment with progesterone and estradiol (PE; producing serum levels observed in the 3rd trimester of pregnancy) or placebo (C) on hepatic and whole body insulin sensitivity and response to hypoglycemia in conscious, overnight-fasted nonpregnant female dogs, using tracer and arteriovenous difference techniques. Insulin was infused peripher...

2006
Alessandro Antonelli Poupak Fallahi Mario Rotondi Silvia Martina Ferrari Paola Romagnani Mariano Grosso Ele Ferrannini Mario Serio

Objective: Serum CXCL10 (an interferon-g-inducible chemokine) levels (sCXCL10) are increased in several autoimmune conditions, including Graves’ disease (GD) and autoimmune thyroiditis (AT). Longitudinal assessment of sCXCL10 in autoimmune hypoor hyperthyroidism has not yet been performed. Design and methods: We longitudinally assayed sCXCL10 in the following groups: 1. thirty-three GD and 11 t...

Journal: :The Biochemical journal 1996
F Schliess R Sinning R Fischer C Schmalenbach D Häussinger

The influence of hypo-osmotic cell swelling on the activity of the mitogen-activated protein (MAP) kinases Erk-1 and Erk-2 (where Erk stands for extracellular signal-regulated protein kinase) was studied in cultured rat astrocytes. Hypo-osmotic treatment led within 10 min to an increased activity of Erk-1 and Erk-2, which became maximal at 20 min and returned to the basal level within 60 min. M...

Journal: :iranian biomedical journal 0
بهرام حقیقی bahram haghighi آزاده مصری پور azadeh mesripour منوچهر مصری پور manouchehr mesripour

the variations of glucose 6-phosphate dehydrogenase (g6pd) activity in different brain regions of normal, hypo- and hyperthyroid rats were investigated. hypo- and hyperthyrodism were experimentaly induced by administration of methimazol and liothyronine, respectively. in normal rats, midbrain had the minimum (70 mu/mg) and cerebral cortex the maximum (349 mu/mg) g6pd activity. hyperthyrodism in...

1986
Edwina L. Rissland Kevin D. Ashley

In this paper we examine the use of hypotheticals as a heuristic device to assist a case-based reasoner test the strengths, weaknesses, and ramifications of an analysis or argument by exploring and augmenting the space of known cases and indirectly, the at tendant spaces of doctrine and argument. Our program, HYPO, works in the task domain of the law, particularly, the area of trade secret prot...

2011
Hiroyuki Yokoyama

he proportion of survival of out-of-hospital cardiac arrest is improving with increased implementation of prompt bystander cardiopulmonary resuscitation (CPR) and early defibrillation; however, the neurologically intact survival for patients of out-of-hospital cardiac arrest still remains low worldwide. Furthermore, development of support measures such as pharmacological circulatory support for...

Journal: :Journal of the American College of Cardiology 2011
Robert Manka Cosima Jahnke Sebastian Kozerke Viton Vitanis Gerard Crelier Rolf Gebker Bernhard Schnackenburg Peter Boesiger Eckart Fleck Ingo Paetsch

OBJECTIVES The aim of this study was to establish a new, dynamic 3-dimensional cardiac magnetic resonance (3D-CMR) perfusion scan technique exploiting data correlation in k-space and time with sensitivity-encoding and to determine its value for the detection of coronary artery disease (CAD) and volumetry of myocardial hypoenhancement (VOLUME(hypo)) before and after percutaneous coronary stentin...

Journal: :Biochimica et biophysica acta 2002
Vivek Kumar Rajendra Prasad

We investigated the effect of thyroid hormone status on renal handing of Ca2+. Further, like kinetics of Ca2+ transport across brush-border membrane (BBM) and basolateral membrane (BLM) of renal epithelial cells was carried out. FE(Ca) was decreased in hyperthyroid (Hyper-T) rats and increased in hypothyroid (Hypo-T) rats as compared to euthyroid (Eu-T) rats. Ca2+ uptake into renal brush-border...

Journal: :The Journal of experimental biology 2014
Joseph D Norman Moira M Ferguson Roy G Danzmann

High-throughput RNA sequencing was used to compare expression profiles in two Arctic charr (Salvelinus alpinus) families post-seawater exposure to identify genes and biological processes involved in hypo-osmoregulation and regulation of salinity tolerance. To further understand the genetic architecture of hypo-osmoregulation, the genomic organization of differentially expressed (DE) genes was a...

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