نتایج جستجو برای: hyperpolarization activiated current if sino atrial node
تعداد نتایج: 1634876 فیلتر نتایج به سال:
1. A scheme is presented which summarizes the activation and deactivation of the membrane currents which underlie pacemaking in the natural pacemaker of the heart. 2. Experimental evidence (mostly obtained using the voltage-clamp technique) for the properties of the time-dependent membrane currents in pacemaking tissue of the frog and the rabbit is discussed. 3. The mode of the inhibitory actio...
BACKGROUND We compared cardiac electrophysiological indicators and regional expression levels of cardiac hyperpolarization-activated cyclic nucleotide-gated (HCN) channels between adult and aged dogs to identify possible mechanisms of age-related atrial fibrillation. MATERIAL/METHODS Corrected sinus node recovery time (SNRTc) and effective refractory period (ERP) of the atrium and pulmonary v...
Heart rate variability (HRV) is a measure of the balance between sympathetic mediators of heart rate that is the effect of epinephrine and norepinephrine released from sympathetic nerve fibres acting on the sino-atrial and atrio-ventricular nodes which increase the rate of cardiac contraction and facilitate conduction at the atrio-ventricular node and parasympathetic mediators of heart rate tha...
Heart rate variability (HRV) is a measure of the balance between sympathetic mediators of heart rate that is the effect of epinephrine and norepinephrine released from sympathetic nerve fibres acting on the sino-atrial and atrio-ventricular nodes which increase the rate of cardiac contraction and facilitate conduction at the atrio-ventricular node and parasympathetic mediators of heart rate tha...
OBJECTIVE The L-type Ca(2+) current (I(Ca,L)) contributes to the generation and modulation of the pacemaker action potential (AP). We investigated facilitation of I(Ca,L) in sino-atrial cells. METHODS Facilitation was studied in regularly-beating cells isolated enzymatically from young albino rabbits (0.8-1 kg). We used the whole-cell patch-clamp technique to vary the frequency of the test de...
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