Hypericum formosanum is a valuable herb in Taiwan. In this study, response surface methodology was employed to optimize the ultrasound-assisted extraction of flavonoids from Hypericum formosanum. A central composite design with three variables (ethanol concentration, extraction time, and extraction temperature) was applied. Experimental results were fitted to the second order polynomial model a...

The value of an extract of Hypericum perforatum (St John's wort) for children with mild to moderate depressive symptoms was investigated for the first time in a multi-centre post-marketing surveillance study. One hundred and one children under 12 years were treated for a minimum of 4 weeks with an extension to 6 weeks with parental consent and medical practitioner recommendation. the dosage use...

background & aim:hypericum perforatum l. is native to iran. this herb is one of the most important medicinal plants and had many medical effects.this experiment was conducted to investigate the effects of feeding hypericum perforatum and protexin on performance, carcass characteristics and intestinal morphology japanese quails. experimental: a total of 240 ten days old quails were divided into ...

The effects of Hypericum perforatum (St John's wort) on morphine withdrawal syndrome and comparison with clonidine have been investigated in morphine-dependent rats. Adult male Wistar rats were subjects. The frequencies of withdrawal behavioral signs (rearing, teeth chattering and jumping) induced by naloxone challenge were demonstrated in morphine dependent rats receiving Hypericum perforatum ...

The overall purpose of this study was to investigate Neurostan Saint John’s Wort (SJW) on the disposition of fexofinadine in the isolated perfused rat liver. SpragueDawley (SD) rats (n = 16) randomized into 3 groups, including: control, low dose (Hypericum, one type of neutostan) and high dose group. Each animal among these groups was pre-treated with either vehicle (ethanol in Milli Q water at...

The work was aimed to develop a method for extraction and identification of the marker compounds of Hypericum species, hyperforin and hypericin present in the buds and leaf extracts of Hypericum hookerianum, a lesser known species of Asia. LC-MS hyphenated techniques were used and the data indicated the presence of both these active compounds in the methanol extract of both buds and leaves. ABT...