BACKGROUND AND PURPOSE Hyperbaric oxygen therapy (HBO) has promise as a treatment for acute stroke. This study was conducted to evaluate the efficacy, safety, and feasibility of using HBO in acute ischemic stroke. METHODS We conducted a randomized, prospective, double-blind, sham-controlled pilot study of 33 patients presenting with acute ischemic stroke who did not receive thrombolytics over...

BACKGROUND Both negative wound pressure therapy (NPWT) and hyperbaric oxygen therapy (HBOT) are useful modalities in the treatment of problem wounds. However, none of the commercially available portable negative-pressure devices have been certified safe for use in a recompression chamber. Thus, the NPWT device is removed while the patient undergoes HBOT. The purpose of this study is to demonstr...

OBJECTIVE We investigated whether hyperbaric oxygen (HBO2) treatment is able to cause any changes in the nasal peak inspiratory flow (NPIF) values of patients submitted to this therapy. STUDY DESIGN NPIF was measured in a group of 13 patients who were submitted to at least 10 sessions of 75 minutes long HBO2 treatments over a period of 20 days. HBO2 was prescribed to the patients to treat hea...

INTRODUCTION Controversy surrounds the use of salvage therapies to treat sudden sensorineural hearing loss (SSNHL), with no consensus on recommendations. While several studies have demonstrated the effectiveness of intratympanic administration of steroids (ITS) and hyperbaric oxygen (HBO) treatment, few have compared the efficacy of ITS and HBO therapy in patients with refractory SSNHL. OBJEC...

OBJECTIVE We conducted a prospective pilot study to assess the safety and efficacy of hyperbaric oxygen (HBO) for the treatment of interstitial cystitis (IC). METHODS Six patients underwent 30 sessions of 100% oxygen inhalation in a hyperbaric chamber and were followed up over 15 months. The measures of efficacy were changes in pain and urgency (visual analog scales), alteration in the patien...

Observations on blood fl ow and metabolism in brain damaged children responding to hyperbaric oxygenation and the world wide clinical findings of its benefit. Purpose The purpose of this presentation is to document the positive clinical changes that are associated with the use of hyperbaric oxygenation in children with cerebral palsy and brain injuries. Summary Cerebral Palsy is a term that enc...

Hypoxia during exercise augments blood flow in active muscles to maintain the delivery of O(2) at normoxic levels. However, the impact of hyperoxia on skeletal muscle blood flow during exercise is not completely understood. Therefore, we tested the hypothesis that the hyperemic response to forearm exercise during hyperbaric hyperoxia would be blunted compared with exercise during normoxia. Seve...

We report the first case of suspected carbon monoxide poisoning treated by hyperbaric oxygen therapy by using a portable hyperbaric stretcher. A 40-year-old British man in Kabul, Afghanistan, was found unresponsive in his apartment. Initial treatment consisted of oxygen by mask at a Combat Support Hospital for several hours, with minimal improvement. Operational security and risk prevented his ...

Trimix (a mixture of helium, nitrogen, and oxygen) has been used in deep diving to reduce the risk of high-pressure nervous syndrome during compression and the time required for decompression at the end of the dive. There is no specific recompression treatment for decompression sickness (DCS) resulting from trimix diving. Our purpose was to validate a rat model of DCS on decompression from a tr...

OBJECTIVES In this study we investigate whether differences exist in human skeletal muscle (MM) and subcutaneous (SC) tissue gas tensions between chronic cigarette smokers and non-smokers measured under room air and hyperbaric conditions. METHODS Gas tensions in resting MM and SC tissues were recorded using a mass spectrometer at four-minute intervals during two and one-half to three-hour per...