BACKGROUND Spinal anesthesia is widely used for caesarean section. Addition of intrathecal magnesium sulfate to local anesthetics seems to improve the quality of block and prolong the duration of analgesia. OBJECTIVES The present study was designed to examine whether addition of intrathecal magnesium sulfate enhances the analgesic efficacy of intrathecal bupivacaine in patients undergoing ces...

BACKGROUND After spinal anesthesia, patients undergoing cesarean section are more likely to develop hemodynamic changes. The baricity of local anesthetic has an important role on spinal blockade effects. The aim of this study was to compare the isobar and hyperbaric bupivacaine 0.5% plus fentanyl on maternal hemodynamics after spinal anesthesia for C/S. METHODS In this double-blind study, 84 ...

CONTEXT Profound side-effects following intrathecal use of local anesthetics as the sole drugs of choice make spinal anesthesia for open appendicectomy uncommon. AIM The aim of this study was to evaluate the effectiveness of intra-operative analgesia produced by intrathecal tramadol and fentanyl during bupivacaine spinal anesthesia for open appendicectomy. SETTINGS AND DESIGN A prospective ...

PURPOSE This study was to evaluate the characteristics of selective spinal anesthesia using 1 mg of bupivacaine combined with fentanyl or sufentanil in elderly patients undergoing transurethral resection of prostate. MATERIALS AND METHODS Fifty-six patients were randomized into two groups. The Fentanyl group received 0.5% hyperbaric bupivacaine 0.2 mL+fentanyl 20 μg+5% dextrose 1.4 mL, and th...

Background; fast track surgery necessitates the use of short-acting anaesthetics with minimum adverse effects. The purpose this study is to assess onset, offset time, and duration motor sensory block after spinal anaesthesia hyperbaric prilocaine 2% or bupivacaine 0.5% added dexmedetomidine during elective inguinal hernia repair surgery. Methods; Participants were randomly allocated using a com...

BACKGROUND Intrathecal ketamine has been studied extensively in animals, but rarely in humans. Intrathecal dexmedetomidine prolongs the duration of spinal anesthesia. OBJECTIVE To investigate the efficacy and safety of intrathecal dexmedetomidine, ketamine, or both when added to bupivacaine for postoperative analgesia in major abdominal cancer surgery. DESIGN Double-blinded, randomized, con...

BACKGROUND AND OBJECTIVES Published data suggest that clonidine, an alpha2-adrenergic agonist, in association with bupivacaine, may increase the incidence of intraoperative hypotension and bradycardia during high-level spinal anesthesia. This study aimed at determining the synergistic potential of two clonidine doses (45 and 75 microg) and hyperbaric bupivacaine on characteristics and hemodynam...

We evaluated four anesthetic techniques for transperineal brachytherapy of the prostate in a day-surgery setting: general anesthesia with either fentanyl and propofol total IV anesthesia (TIVA) or with fentanyl, thiopental, and isoflurane (F-P-I), versus spinal block using 5 mg of 0.5% large-dose spinal hyperbaric bupivacaine (LDS) or 2.5 mg of 0.5% hyperbaric bupivacaine plus fentanyl 25 mug s...

Introduction: This single-center, prospective, randomized, double-blind study compares the effect of intrathecal fentanylbupivacaine and tramadol-bupivacaine on the onset and duration of sensory and motor blockade, as well as postoperative analgesia in lower abdominal surgeries. Materials and methods: Patients of either sex, aged 18 to 60 years, American Society of Anesthesiologists (ASA) grade...

conclusions dexmedetomidine added to bupivacaine in spinal anesthesia is more effective to increase duration of block, providing more appropriate sedation and less postoperative pain scale and post-operative nausea and vomiting (ponv) compared to fentanyl additive. results totally, 84 patients were randomly divided into three groups of 28 patients. onset of sensory block in dex group was signif...