cases with hirschsprung’s disease show the functional intestinal obstruction. obstruction in these patients may lead to bacterial overgrowth with stasis and inflammation of the colon. bacterial overgrowth can cause hyperammonemia that makes lethargy and loss of conscious and finally admitting in icu. the purpose of this case report is to present a case that had hirschsprung’s disease and referr...

The cerebral tricarboxylic acid (TCA) cycle rate and the rate of glutamine synthesis were measured in rats in vivo under normal physiological and hyperammonemic conditions using 13C NMR spectroscopy. In the hyperammonemic animals, blood ammonia levels were raised from control values of approximately 0.05 mM to approximately 0.35 mM by an intravenous ammonium acetate infusion. Once a steady-stat...

this report details the presence of hyperammonemia in a patient who sustained cardiac arrest after a traumatic amputation. serum ammonia levels may rise due to numerous etiologies; however, few reports detail its usefulness in diagnosing subclinical seizures. in this case, we successfully utilized persistently elevated serum ammonia levels as a marker of subclinical seizures in a patient who su...

Epidemiological data suggests that approximately 10-65% of patients with mild to moderate COVID-19 have persistent symptoms already after an acute infection, which may last for six months or more. Previous clinical studies shown similar also occur in the liver. Russian scientists studied phenomenon hyperammonemia phase COVID-19, but problem elevated blood ammonia levels post - COVID syndrome ha...

Symptoms of hyperammonemia are age-dependent and some are reversible. Multiple mechanisms are involved. Hyperammonemia increases the uptake of tryptophan into the brain by activation of the L-system carrier while brain glutamine plays a still undefined role. The uptake of tryptophan by the brain is enhanced when the plasma levels of branched-chain amino acids competing with the other large neut...