Vitamin D deficiency is a growing health problem in both the general population and in patients with chronic kidney disease (CKD). However, the relationship between serum 25-hydroxyvitamin D levels and health-related quality of life in CKD is not well established. This study examined the association between vitamin D deficiency and quality of life in pre-dialysis CKD patients. Serum 25-hydroxyv...

The active form of vitamin D is 1,25 dihydroxy D. Renal and many extra renal tissues are able to synthesize on a local intracellular level. Local tissue level di-hydroxyvitamin determined by concentration circulating 25(OH) Stroke common worldwide health problem. It major cause morbidity, mortality disability in developed as well developing countries. Both deficiency stroke very urban rural Ind...

BACKGROUND Exposure to low levels of vitamin D in fetal life might be a risk factor for childhood asthma. OBJECTIVE We examined whether 25-hydroxyvitamin D levels in mid-gestation and at birth were associated with higher airway resistance and inflammation, and increased risks of wheezing and asthma in school-age children. METHODS We performed a population-based prospective cohort study amon...

BACKGROUND The bioavailability of vitamin D from mushrooms in humans is unknown. OBJECTIVE We investigated the bioavailability of vitamin D from wild edible mushrooms (Cantharellus tubaeformis) using the increase in serum 25-hydroxyvitamin D concentrations as a measure of vitamin D bioavailability. DESIGN Twenty-seven volunteers with serum 25-hydroxyvitamin D concentrations <60 nmol/L (mean...

BACKGROUND AND PURPOSE Vitamin D deficiency is common across all age groups and may contribute to cardiovascular diseases. Serum 25-hydroxyvitamin D deficiency causing ischemic stroke has been documented in recent reports. AIM To investigate the association of serum 25-hydroxyvitamin D deficiency with ischemic stroke and subtypes. METHODS We recruited 250 consecutive ischemic stroke patient...

CONTEXT A number of controversies exist regarding appropriate treatment strategy for Vitamin D deficiency. AIMS The aim of this study was to investigate the efficacy of equivalent doses of oral cholecalciferol (60,000 IU weekly for 5 weeks) versus intramuscular (IM) cholecalciferol (300,000 IU) in correcting Vitamin D deficiency in apparently healthy volunteers working in a hospital. SETTIN...

CONTEXT Studies examining vitamin D levels in association with childhood obesity usually do not consider the effect of insulin on vitamin D-binding protein and do not calculate the unbound, bioavailable vitamin D. OBJECTIVE This study aimed to evaluate in a group of children 1) the concentrations of both total 25-hydroxyvitamin D and bioavailable fraction, and 2) the potential role of insulin...

Graves disease is the most common cause of thyrotoxicosis. Although medical intervention with antithyroid drugs (ATDs) is commonly the first choice of treatment in Korea, the remission rate associated with this approach is not satisfactory. During ATD therapy, low or undetectable serum levels of thyroid-stimulating hormone (TSH) receptor antibodies (TRAbs) have been reported to affect the incid...

BACKGROUND In general, no study has examined the relationship between vitamin D status and key parameters of bone mineral homeostasis in healthy men in Iran. The effects of age and renal function on vitamin D status were determined in a cross-sectional study on a healthy population of Iranian men. METHODS From January through February 2001, 520 men, aged 20 - 74 years were selected through a ...