Different non-ionic cellulose ethers (methyl cellulose, MC; hydroxyethyl cellulose, HEC; hydroxypropyl cellulose, HPC; hydroxypropylmethyl cellulose, HPMC) and microcrystalline cellulose (MCC) were investigated as matrix formers for preparation of mini-tablets targeting vaginal drug delivery. Hexyl aminolevulinat hydrochloridum (HAL) was used as a model drug. The mini-tablets were characterized...

Hydroxypropyl methylcellulose (HPMC) is a polymer made of cellulose backbone with etherified methoxy and hydroxypropyl substitutions that undergoes reversible inverse thermo-gelation upon heating. The follows two-step mechanism: first, phase separation occurs, then fibrils, formed in the polymer-rich phase, entangle to form three-dimensional gel network. This work aims at understanding influenc...

Prostate cancer (PC) is the most frequently diagnosed disease in men in the United States. Curcumin (CUR), a natural diphenol, has shown potent anti-cancer efficacy in various types of cancers. However, suboptimal pharmacokinetics and poor bioavailability limit its effective use in cancer therapeutics. Several successful CUR nanoformulations have recently been reported which improve upon these ...

The possibility of increasing the strength and operational properties ecologically safe biodegradable polymeric materials based on hydroxypropyl methyl cellulose by using its modification with different types humic acids (HAs) from lignite is considered. Hybrid high-strength films antibacterial were obtained for first time. Physicochemical studies IR spectroscopy confirmed development hybrid st...

The purpose of this study was to improve the operability of calcium silicate cements (CSCs) such as mineral trioxide aggregate (MTA) cement. The flow, working time, and setting time of CSCs with different compositions containing low-viscosity methyl cellulose (MC) or hydroxypropyl cellulose (HPC) additive were examined according to ISO 6876-2012; calcium ion release analysis was also conducted....

Cellulose based polymers have shown tremendous potential as drug delivery carrier for oral drug delivery system (DDS). Hydroxyethyl cellulose (HEC) and hydroxypropyl cellulose (HPC) are widely explored as excipients to improve the solubility of poorly water soluble drugs and to improve self-life of dosage form. This work is an attempt to modulate the physicochemical properties of these cellulos...

Oil palm empty fruit bunches (OPEFB) can be used as raw material for Hydroxypropyl Methylcellulose (HPMC). HPMC a French fries coating to reduce oil uptake. This research aims study the utilization of OPEFB coating. consists two stages. The first stage is cellulose extraction and synthesis. synthesis through alkalization, methylation, propylation, neutralization. second use with different conce...