Summa(iry. Hlydroxy-L-proline-induced inhiibition of elongationi of Aven(a coleoptile segments was measuired in water and in indole-3-acetic aci(l. This inhibition was completely reversed by L-proline. Time-sequence experiments revealed that some time had to elapse, or some eloingationi had to occur, prior to the onset of hydroxyproline inhibition. The presence of sucrose supported the rate of ...

One of the earliest detectable events during plant-pathogen interaction is a rapid increase in ethylene biosynthesis. This gaseous plant stress hormone may be a signal for plants to activate defense mechanisms against invading pathogens such as bacteria, fungi, and viruses. The effect of ethylene on four plant genes involved in three separate plant defense response pathways was examined; these ...

et al., 1967; Zorab et al., 1970). Allison, Walker, and Smith (1966) showed that the ratio of total hydroxyproline to creatinine in a 24-hour collection of urine gives more consistent results than measurement of hydroxyproline alone, an observation which has been extended to random samples of urine collected during waking hours (Howells, Wharton, and McCance, 1967; Younoszai et al., 1969). Whar...

There is a unique relationship between proline hydroxylation and collagen biosynthesis, since proline, rather than free hydroxyproline, appears to be the major precursor of collagen hydroxyproline (1, 2). The early stages of collagen biosynthesis have been shown to be similar to the steps involved in the biosynthesis of other proteins in that hydroxyproline with the highest specific activity ap...

silymarin, an extract from silybum marianum, has been shown to have antioxidant properties. however, there is no scientific report on wound healing activity of the silymarin. the purpose of this study was to evaluate the effect of topical administration of silymarin on excision wound healing in rats. excision wounds were made on the back of rats. rats were divided into three groups, as control,...

I . The amounts of available cystine and tyrosine in the protein of different animal tissues showed a close correlation with the level of hydroxyproline, and may be estimated from hydroxyproline values by regression equations. 2. Estimates of ‘chemical score’ have been calculated from the content of hydroxyproline determined in a series of samples for which net protein utilization (NPIJ) for ra...

1. Plasma alkaline phosphatase activity and urine hydroxyproline excretion were measured in age-matched premenopausal and postmenopausal women. 2. Both measurements were found to be significantly higher in postmenopausal women. 3. It is proposed that the rise in the plasma alkaline phosphatase, like that in the hydroxyproline excretion, may reflect the onset of bone loss that occurs after the m...

There is a unique relationship between proline hydroxylation and collagen biosynthesis, since proline, rather than free hydroxyproline, appears to be the major precursor of collagen hydroxyproline (1, 2). The early stages of collagen biosynthesis have been shown to be similar to the steps involved in the biosynthesis of other proteins in that hydroxyproline with the highest specific activity ap...